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 Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions: 

Indicate by check mark whether the registrant is an emerging growth company as defined in Rule 405 of the Securities Act of 1933 (§230.405 of this chapter) or Rule 12b-2 of the Securities Exchange Act of 1934 (§240.12b-2 of this chapter).

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On April 3, 2024, the board of directors (the “Board”) of Alpine Immune Sciences, Inc. (the “Company”), appointed U. Martin Fuhs as its Chief Accounting Officer and principal accounting officer. Mr. Fuhs has served as the Company’s Vice President, Finance since November 2021 and will continue to serve the Company in such role. Mr. Fuhs succeeds Paul Rickey, the Company’s Senior Vice President, Chief Financial Officer, and Corporate Secretary, in the role of principal accounting officer. Mr. Rickey will continue to serve as the Company’s Senior Vice President, Chief Financial Officer, Corporate Secretary, and Treasurer, as well as the Company’s principal financial officer.

Prior to joining the Company, Mr. Fuhs, age 56, served as Chief Accounting Officer of Holland America/Princess Cruises Group for Carnival Corporation from May 2018 to January 2021. In total, Mr. Fuhs has almost 30 years of experience in auditing and financial reporting roles, including management positions with KPMG LLP, Public Storage, Inc., Plum Creek Timber Company, Inc. and T-Mobile US, Inc. Mr. Fuhs received his Masters of Economics degree from the University of Bonn in Germany and is a certified public accountant in Washington State.

There are no family relationships between Mr. Fuhs and any director or executive officer of the Company and he has no direct or indirect material interest in any transaction or proposed transaction required to be disclosed pursuant to Item 404(a) of Regulation S-K. There also is no arrangement or understanding between Mr. Fuhs and any other person or entity pursuant to which Mr. Fuhs was appointed as Chief Accounting Officer and principal accounting officer of the Company.

The Company will enter into its standard form of indemnification agreement with Mr. Fuhs.

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.