エドガーで原本を確認する
UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, DC 20549
FORM 8-K
CURRENT REPORT
Pursuant to Section 13 or 15(d) of
The Securities Exchange Act of 1934
Date of Report (Date of earliest event reported): August 6, 2025
MaxCyte, Inc.
(Exact name of registrant as specified in its charter)
Delaware |
|
001-40674 |
|
52-2210438 |
(State or other jurisdiction of |
|
(Commission File Number) |
|
(IRS Employer |
9713 Key West Avenue, Suite 400
Rockville, Maryland 20850
(Address of principal executive offices, including zip code)
(301) 944-1700
(Registrant’s telephone number, including area code)
N/A
(Former name or former address, if changed since last report)
Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions:
☐ Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)
☐ Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)
☐ Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))
☐ Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))
Securities registered pursuant to Section 12(b) of the Act:
Title of each class |
|
Trading |
|
Name of each exchange |
Common Stock, $0.01 par value |
|
MXCT |
|
The Nasdaq Stock Market LLC |
Indicate by check mark whether the registrant is an emerging growth company as defined in Rule 405 of the Securities Act of 1933 (§230.405 of this chapter) or Rule 12b-2 of the Securities Exchange Act of 1934 (§240.12b-2 of this chapter).
Emerging growth company ☒
If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial account standards provided pursuant to Section 13(a) of the Exchange Act. ☐
Item 2.02. Results of Operations and Financial Condition.
On August 6, 2025, MaxCyte, Inc. (the “Company”) issued a press release announcing its financial results for the quarter and six months ended June 30, 2025. A copy of this press release is furnished as Exhibit 99.1 to this Current Report on Form 8-K and is incorporated herein by reference.
The information in this Current Report on Form 8-K, including Exhibit 99.1 hereto, is furnished and shall not be deemed “filed” for purposes of Section 18 of the Securities Exchange Act of 1934, as amended (the “Exchange Act”) or otherwise subject to the liabilities of that section. The information contained herein and in the accompanying exhibit is not incorporated by reference in any filing of the Company under the Securities Act of 1933, as amended, or the Exchange Act, whether made before or after the date hereof and irrespective of any general incorporation language in any filings, except as expressly set forth by specific reference in such a filing.
Item 7.01. Regulation FD Disclosure.
On August 6, 2025, the Company posted an updated corporate presentation, which the Company may use from time to time in communications or conferences, to its website at https://investors.maxcyte.com. A copy of the corporate presentation is furnished as Exhibit 99.2 to this Current Report on Form 8-K and is incorporated herein by reference.
The information in this Current Report on Form 8-K, including Exhibit 99.2 hereto, is furnished and shall not be deemed “filed” for purposes of Section 18 of the Exchange Act or otherwise subject to the liabilities of that section. The information contained herein and in the accompanying exhibit is not incorporated by reference in any filing of the Company under the Securities Act of 1933, as amended, or the Exchange Act, whether made before or after the date hereof and irrespective of any general incorporation language in any filings, except as expressly set forth by specific reference in such a filing.
Item 9.01. Financial Statements and Exhibits.
(d) Exhibits
Exhibit |
|
Exhibit Description |
|
|
|
99.1 |
|
|
99.2 |
|
|
104 |
|
Cover Page Interactive Data (embedded within the Inline XBRL document) |
SIGNATURES
Pursuant to the requirements of the Securities Exchange Act of 1934, as amended, the Registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.
|
MaxCyte, Inc. |
|
|
|
|
Dated: August 6, 2025 |
By: |
/s/ Douglas Swirsky |
|
|
Douglas Swirsky |
|
|
Chief Financial Officer |
Exhibit 99.1
MaxCyte Reports Second Quarter 2025 Financial Results and Updates Full Year 2025 Guidance
ROCKVILLE, MD, August 6, 2025 — MaxCyte, Inc., (NASDAQ: MXCT), a leading, cell-engineering focused company providing enabling platform technologies to advance the discovery, development and commercialization of next-generation cell therapeutics, today announced its second quarter ended June 30, 2025 financial results and updated its 2025 guidance.
Second Quarter and Recent Highlights
· |
Core business revenue of $8.2 million in the second quarter of 2025, an increase of 8% over the second quarter of 2024. |
· |
Strategic Platform License SPL Program-related revenue was $0.3 million for the second quarter of 2025, compared to $2.9 million in the second quarter of 2024, reflecting the timing variability of SPL Program-related revenue milestones and royalties. |
· |
Total revenue of $8.5 million in the second quarter of 2025, a decrease of 18% over the second quarter of 2024. |
· |
MaxCyte added two new SPL clients, Adicet Bio and Anocca AB, in July. Including TG Therapeutics signed in the first quarter, the total number of SPLs agreements stands at 31. |
· |
Total cash, cash equivalents and investments were $165.2 million as of June 30, 2025. The decrease in cash, cash equivalents and investments since the beginning of the year includes approximately $7.0 million of purchase, transaction, and one-time costs to acquire SeQure Dx. |
“Despite solid growth in the first half of 2025, the operating environment has evolved since the beginning of the year, impacting our expectations for the second half of 2025. We are lowering our 2025 guidance to account for customer inventory management, as well as some reprioritization and consolidation of customer pipelines. While disappointed with the short-term headwinds, we continue to remain focused on executing in this environment, supporting customers with excellent technology and service,” said Maher Masoud, President and CEO of MaxCyte. “Our pipeline of potential SPLs remains strong, demonstrated by the two new SPLs that we recently announced, Adicet Bio and Anocca AB, bringing our total number of SPL agreements to 31. We continue to be confident about the opportunity in the cell and gene therapy industry and our position in it, remaining committed to spending prudently, and investing in product enhancements and SeQure Dx. We are confident that with improving operational efficiencies, multiple product offerings, and maturing clinical programs of our customers, we will achieve profitability with our existing capital.”
1
The following tables provide details regarding the sources of the Company’s revenue for the periods presented.
|
|
Three Months Ended |
|
|
|
||||
|
|
June 30 |
|
|
|
||||
|
|
(Unaudited) |
|
|
|
||||
|
|
2025 |
|
2024 |
|
% Change |
|
||
(in thousands, except percentages) |
|
|
|
|
|
|
|
||
Instruments |
|
$ |
2,141 |
|
$ |
1,762 |
|
22 |
% |
PAs and consumables |
|
|
3,128 |
|
|
2,974 |
|
5 |
% |
Licenses |
|
|
2,619 |
|
|
2,610 |
|
0 |
% |
Assay services |
|
|
51 |
|
|
— |
|
— |
|
Other |
|
|
259 |
|
|
229 |
|
13 |
% |
Total Core Revenue |
|
$ |
8,198 |
|
$ |
7,575 |
|
8 |
% |
Program-Related |
|
|
309 |
|
|
2,854 |
|
(89) |
% |
Total Revenue |
|
$ |
8,507 |
|
$ |
10,429 |
|
(18) |
% |
In addition to revenue, management regularly reviews key business metrics to evaluate our business, measure performance, identify trends affecting our business, formulate financial projections and make strategic decisions. As of the dates presented, these key metrics were as follows:
|
|
Three Months Ended |
|
||
|
|
June 30, |
|
||
|
|
2025 |
|
2024 |
|
Installed base of instruments (sold or leased) |
|
814 |
|
723 |
|
Core Revenue Generated by SPL Clients as a % of Core Revenue |
|
42 |
% |
51 |
% |
Second Quarter 2025 Financial Results
Total revenue for the second quarter of 2025 was $8.5 million, compared to $10.4 million in the second quarter of 2024, representing a decrease of 18%.
Core business revenue (sales of instruments, PAs and consumables, assay services, and licenses to customers, excluding SPL Program-related revenue) for the second quarter of 2025 was $8.2 million, compared to $7.6 million in the second quarter of 2024, representing an increase of 8%.
SPL Program-related revenue was $0.3 million in the second quarter of 2025, as compared to $2.9 million in the second quarter of 2024.
Gross profit for the second quarter of 2025 was $7.0 million (82% gross margin), compared to $8.9 million (86% gross margin) in the second quarter of 2024. Non-GAAP adjusted gross margin was 83% excluding SPL Program-related revenue and reserves for excess and obsolete inventory, compared to non-GAAP adjusted gross margin of 82% in the second quarter of 2024.
Operating expenses for the second quarter of 2025 were $21.2 million, compared to operating expenses of $20.9 million in the second quarter of 2024.
Second quarter 2025 net loss was $12.4 million compared to net loss of $9.4 million for the same period in 2024. EBITDA, a non-GAAP measure, was a loss of $13.1 million for the second quarter of 2025, compared to a loss of $10.9 million for the second quarter of 2024; stock-based compensation expense was $3.5 million in the second quarter of 2025 compared to $3.6 million in the second quarter of 2024.
2
2025 Guidance
MaxCyte updates 2025 revenue guidance for core business revenue and SPL Program-related revenue:
· |
Core revenue is expected to be flat to a 10% decline compared to 2024, inclusive of revenue from SeQure Dx. |
· |
SPL Program-related revenue is expected to be approximately $5 million for the year. SPL-program related revenue guidance includes both expected revenue from pre-commercial milestone payments and commercial royalties/sales-based payments. |
MaxCyte now expects to end 2025 with at least $155 million in total cash, cash equivalents and investments.
Webcast and Conference Call Details
MaxCyte will host a conference call today, August 6, 2025, at 4:30 p.m. Eastern Time. Investors interested in listening to the conference call are required to register online. A live and archived webcast of the event will be available on the “Events” section of the MaxCyte website at https://investors.maxcyte.com/.
About MaxCyte
At MaxCyte®, we are committed to building better cells together. As a leading cell-engineering company, we are driving the discovery, development and commercialization of next-generation cell therapies. Our best-in-class Flow Electroporation® technology and SeQure DX™ gene editing risk assessment services enable precise, efficient and scalable cell engineering. Supported by expert scientific, technical and regulatory guidance, our platform empowers researchers from around the world to engineer diverse cell types and payloads, accelerating the development of safe and effective treatments for human health. For more than 25 years, we’ve been advancing cell engineering, shaping the future of medicine. Learn more at maxcyte.com and follow us on X and LinkedIn.
Non-GAAP Financial Measures
This press release contains EBITDA, which is a non-GAAP measure defined as earnings before interest income and expense, taxes, depreciation and amortization. MaxCyte believes that EBITDA provides useful information to management and investors relating to its results of operations. The company’s management uses this non-GAAP measure to compare the company’s performance to that of prior periods for trend analyses, and for budgeting and planning purposes. The company believes that the use of EBITDA provides an additional tool for investors to use in evaluating ongoing operating results and trends and in comparing the company’s financial measures with other companies, many of which present similar non-GAAP financial measures to investors, and that it allows for greater transparency with respect to key metrics used by management in its financial and operational decision-making.
This press release also contains Non-GAAP Gross Margin, which we define as Gross Margin when excluding SPL program related revenue and reserves for excess and obsolete inventory. The Company believes that the use of Non-GAAP Gross Margin provides an additional tool to investors because it provides consistency and comparability with past financial performance, as Non-GAAP Gross Margin excludes non-core revenues and inventory reserves, which can vary significantly between periods and thus affect comparability.
Management does not consider these Non-GAAP financial measures in isolation or as an alternative to financial measures determined in accordance with GAAP. The principal limitation of these Non-GAAP financial measures is that they exclude significant revenues and expenses that are required by GAAP to be recorded in the Company’s financial statements. In order to compensate for these limitations, management presents these Non-GAAP financial measures along with GAAP results. Non-GAAP measures should be considered in addition to results prepared in accordance with GAAP, but should not be considered a substitute for, or superior to, GAAP results.
3
Reconciliation tables of net loss, the most comparable GAAP financial measure, to EBITDA, and Gross Margin, the most comparable GAAP financial measure, to Non-GAAP Gross Margin, are included at the end of this release. MaxCyte urges investors to review the reconciliation and not to rely on any single financial measure to evaluate the company’s business
Forward-Looking Statements
This press release contains “forward-looking statements” within the meaning of the “safe harbor” provisions of the Private Securities Litigation Reform Act of 1995. These statements about us and our industry involve substantial known and unknown risks, uncertainties, and assumptions, including those described in Item 1A under the heading “Risk Factors” and elsewhere in our report on Form 10-K, that may cause our actual results, performance or achievements to be materially different from any future results, performance or achievements expressed or implied by the forward-looking statements. All statements other than statements of historical facts contained in this press release, including statements regarding our future results of operations or financial condition, business strategy and plans and objectives of management for future operations, are forward-looking statements. Forward-looking statements include, but are not limited to, statements about the Company’s preliminary results of operations, including fourth quarter and full year total revenue, core revenue, and SPL program revenue and statements about possible or future results of operations or financial position. In some cases, you can identify forward-looking statements because they contain words such as “may,” “might,” “will,” “could,” “would,” “should,” “expect,” “plan,” “anticipate,” “intend,” “believe,” “expect,” “estimate,” “seek,” “predict,” “future,” “project,” “potential,” “continue,” “contemplate,” “target,” the negative of these words and similar words or expressions. These statements are inherently uncertain, and investors are cautioned not to unduly rely on these statements. The forward-looking statements contained in this press release, include, without limitation, statements concerning the following: our expected future growth and success of our business model; the size and growth potential of the markets for our products, and our ability to serve those markets, increase our market share, and achieve and maintain industry leadership; our ability to expand our customer base and enter into additional SPL partnerships; our expectation that our partners will have access to capital markets to develop and commercialize their cell therapy programs; our financial performance and capital requirements; the adequacy of our cash resources and availability of financing on commercially reasonable terms; our expectations regarding our ability to obtain and maintain intellectual property protection for our products, as well as our ability to operate our business without infringing the intellectual property rights of others; our expectations regarding general market and economic conditions that may impact investor confidence in the biopharmaceutical industry and affect the amount of capital such investors provide to our current and potential partners; and our use of available capital resources.
4
These and other risks and uncertainties are described in greater detail in Item 1A , entitled “Risk Factors,” in our Annual Report on Form 10-K for the year ended December 31, 2024, filed with the Securities and Exchange Commission on March 11, 2025, as well as in discussions of potential risks, uncertainties, and other important factors in the other filings that we make with the Securities and Exchange Commission from time to time. These documents are available through the Investor Menu, Financials section, under “SEC Filings” on the Investors page of our website at http://investors.maxcyte.com. Any forward-looking statements in this press release are based on our current beliefs and opinions on the relevant subject based on information available to us as of the date of such press release, and you should not rely on forward-looking statements as predictions of future events. We undertake no obligation to update any forward-looking statements made in this press release to reflect events or circumstances after the date of this press release or to reflect new information or the occurrence of unanticipated events, except as required by law.
MaxCyte Contacts:
Investor Relations
Gilmartin Group
David Deuchler, CFA
+1 415-937-5400
ir@maxcyte.com
Media Contact
Oak Street Communications
Kristen White
kristen@oakstreetcommunications.com
415.608.6060
5
MaxCyte, Inc.
Unaudited Consolidated Balance Sheets
(in thousands, except share and per share amounts)
|
|
June 30, 2025 |
|
December 31, 2024 |
|
||
Assets |
|
|
|
|
|
|
|
Current assets: |
|
|
|
|
|
|
|
Cash and cash equivalents |
|
$ |
15,225 |
|
$ |
27,884 |
|
Short-term investments, at amortized cost |
|
|
111,337 |
|
|
126,598 |
|
Accounts receivable, net |
|
|
5,753 |
|
|
4,682 |
|
Inventory |
|
|
7,933 |
|
|
8,914 |
|
Prepaid expenses and other current assets |
|
|
2,971 |
|
|
3,606 |
|
Total current assets |
|
|
143,219 |
|
|
171,684 |
|
|
|
|
|
|
|
|
|
Investments, non-current, at amortized cost |
|
|
38,600 |
|
|
35,781 |
|
Property and equipment, net |
|
|
19,404 |
|
|
19,707 |
|
Right-of-use asset - operating leases |
|
|
11,344 |
|
|
10,766 |
|
Goodwill |
|
|
3,748 |
|
|
— |
|
Intangible assets, net |
|
|
638 |
|
|
— |
|
Other assets |
|
|
2,797 |
|
|
1,532 |
|
Total assets |
|
$ |
219,750 |
|
$ |
239,470 |
|
|
|
|
|
|
|
|
|
Liabilities and stockholders’ equity |
|
|
|
|
|
|
|
Current liabilities: |
|
|
|
|
|
|
|
Accounts payable |
|
$ |
1,210 |
|
$ |
1,358 |
|
Accrued expenses and other |
|
|
6,397 |
|
|
8,302 |
|
Operating lease liability, current |
|
|
1,308 |
|
|
864 |
|
Deferred revenue, current portion |
|
|
2,640 |
|
|
5,251 |
|
Total current liabilities |
|
|
11,555 |
|
|
15,775 |
|
|
|
|
|
|
|
|
|
Operating lease liability, net of current portion |
|
|
17,199 |
|
|
17,170 |
|
Contingent consideration |
|
|
25 |
|
|
— |
|
Other liabilities |
|
|
248 |
|
|
274 |
|
Total liabilities |
|
|
29,027 |
|
|
33,219 |
|
|
|
|
|
|
|
|
|
Commitments and contingencies |
|
|
|
|
|
|
|
Stockholders’ equity |
|
|
|
|
|
|
|
Preferred stock, $0.01 par value; 5,000,000 shares authorized and no shares issued and outstanding at June 30, 2025 and December 31, 2024 |
|
|
— |
|
|
— |
|
Common stock, $0.01 par value; 400,000,000 shares authorized, 106,592,139 and 105,711,093 shares issued and outstanding at June 30, 2025 and December 31, 2024, respectively |
|
|
1,066 |
|
|
1,057 |
|
Additional paid-in capital |
|
|
429,128 |
|
|
422,047 |
|
Accumulated deficit |
|
|
(239,471) |
|
|
(216,853) |
|
Total stockholders’ equity |
|
|
190,723 |
|
|
206,251 |
|
Total liabilities and stockholders’ equity |
|
$ |
219,750 |
|
$ |
239,470 |
|
6
MaxCyte, Inc.
Unaudited Consolidated Statements of Operations
(in thousands, except share and per share amounts)
|
|
Three Months Ended June 30, |
|
Six Months Ended June 30, |
|
||||||||
|
|
2025 |
|
2024 |
|
2025 |
|
2024 |
|
||||
Revenue |
$ |
8,507 |
$ |
10,429 |
$ |
18,897 |
$ |
21,770 |
|
||||
Cost of goods sold |
|
|
1,519 |
|
|
1,488 |
|
|
3,016 |
|
|
2,891 |
|
Gross profit |
|
|
6,988 |
|
|
8,941 |
|
|
15,881 |
|
|
18,879 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Operating expenses: |
|
|
|
|
|
|
|
|
|
|
|
|
|
Research and development |
|
|
6,269 |
|
|
5,619 |
|
|
12,172 |
|
|
12,297 |
|
Sales and marketing |
|
|
5,786 |
|
|
6,617 |
|
|
11,484 |
|
|
13,981 |
|
General and administrative |
|
|
8,080 |
|
|
7,639 |
|
|
16,606 |
|
|
14,742 |
|
Depreciation and amortization |
|
|
1,080 |
|
|
1,034 |
|
|
2,141 |
|
|
2,102 |
|
Total operating expenses |
|
|
21,215 |
|
|
20,909 |
|
|
42,403 |
|
|
43,122 |
|
Operating loss |
|
|
(14,227) |
|
|
(11,968) |
|
|
(26,522) |
|
|
(24,243) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Other income: |
|
|
|
|
|
|
|
|
|
|
|
|
|
Interest income |
|
|
1,870 |
|
|
2,593 |
|
|
3,904 |
|
|
5,342 |
|
Total other income |
|
|
1,870 |
|
|
2,593 |
|
|
3,904 |
|
|
5,342 |
|
Net loss |
|
$ |
(12,357) |
|
$ |
(9,375) |
|
$ |
(22,618) |
|
$ |
(18,901) |
|
Basic and diluted net loss per share |
|
$ |
(0.12) |
|
$ |
(0.09) |
|
$ |
(0.21) |
|
$ |
(0.18) |
|
Weighted average shares outstanding, basic and diluted |
|
|
106,403,540 |
|
|
104,639,239 |
|
|
106,178,262 |
|
|
104,364,498 |
|
7
MaxCyte, Inc.
Unaudited Consolidated Statements of Cash Flows
(in thousands)
|
|
Six Months ended June 30, |
|
||||
|
|
2025 |
|
2024 |
|
||
Cash flows from operating activities: |
|
|
|
|
|
|
|
Net loss |
|
$ |
(22,618) |
|
$ |
(18,901) |
|
|
|
|
|
|
|
|
|
Adjustments to reconcile net loss to net cash used in operating activities: |
|
|
|
|
|
|
|
Depreciation and amortization |
|
|
2,196 |
|
|
2,192 |
|
Lease right-of-use asset amortization |
|
|
378 |
|
|
233 |
|
Net book value of consigned equipment sold |
|
|
55 |
|
|
21 |
|
Loss on disposal of property and equipment |
|
|
113 |
|
|
361 |
|
Stock-based compensation |
|
|
6,553 |
|
|
6,579 |
|
Credit loss expense (recovery) |
|
|
10 |
|
|
(130) |
|
Change in excess/obsolete inventory reserve |
|
|
165 |
|
|
137 |
|
Amortization of discounts on investments |
|
|
(1,635) |
|
|
(3,665) |
|
|
|
|
|
|
|
|
|
Changes in operating assets and liabilities, net of effects of acquisition: |
|
|
|
|
|
|
|
Accounts receivable |
|
|
(1,077) |
|
|
1,327 |
|
Inventory |
|
|
754 |
|
|
833 |
|
Prepaid expense and other current assets |
|
|
773 |
|
|
1,322 |
|
Other assets |
|
|
(1,140) |
|
|
(321) |
|
Accounts payable, accrued expenses and other |
|
|
(5,340) |
|
|
(3,497) |
|
Operating lease liability |
|
|
(593) |
|
|
(215) |
|
Deferred revenue |
|
|
(2.831) |
|
|
(1,701) |
|
Other liabilities |
|
|
(26) |
|
|
27 |
|
Net cash used in operating activities |
|
|
(24,263) |
|
|
(15,398) |
|
|
|
|
|
|
|
|
|
Cash flows from investing activities: |
|
|
|
|
|
|
|
Purchases of investments |
|
|
(63,523) |
|
|
(79,353) |
|
Maturities of investments |
|
|
77,600 |
|
|
85,440 |
|
Purchases of property and equipment |
|
|
(1,237) |
|
|
(1,098) |
|
Acquisition of business, net of cash acquired of $541 |
|
|
(1,773) |
|
|
— |
|
Net cash provided by investing activities |
|
|
11,067 |
|
|
4,989 |
|
|
|
|
|
|
|
|
|
Cash flows from financing activities: |
|
|
|
|
|
|
|
Proceeds from exercise of stock options |
|
|
403 |
|
|
1,151 |
|
Proceeds from issuance of common stock under employee stock purchase plan |
|
|
134 |
|
|
265 |
|
Net cash provided by financing activities |
|
|
537 |
|
|
1,416 |
|
Net decrease in cash and cash equivalents |
|
|
(12,659) |
|
|
(8,993) |
|
Cash and cash equivalents, beginning of period |
|
|
27,884 |
|
|
46,506 |
|
Cash and cash equivalents, end of period |
|
$ |
15,225 |
|
$ |
37,513 |
|
8
Unaudited Reconciliation of Net Loss to EBITDA
(in thousands)
(Unaudited)
|
|
Three Months Ended |
|
Six Months Ended |
|
||||||||
|
|
June 30, |
|
June 30, |
|
||||||||
|
|
2025 |
|
2024 |
|
2025 |
|
2024 |
|
||||
(in thousands) |
|
|
|
|
|
|
|
|
|
||||
Net loss |
|
$ |
(12,357) |
|
$ |
(9,375) |
|
$ |
(22,618) |
|
$ |
(18,901) |
|
Depreciation and amortization expense |
|
|
1,100 |
|
|
1,081 |
|
|
2,196 |
|
|
2,192 |
|
Interest income |
|
|
(1,870) |
|
|
(2,593) |
|
|
(3,904) |
|
|
(5,342) |
|
Income taxes |
|
|
— |
|
|
— |
|
|
— |
|
|
— |
|
EBITDA |
|
$ |
(13,127) |
|
$ |
(10,887) |
|
$ |
(24,326) |
|
$ |
(22,051) |
|
9
Unaudited Reconciliation of Gross Margin to Non-GAAP Adjusted gross margin
(in thousands, except for percentages)
(Unaudited)
|
|
Three months ended June 30, 2025 |
|
Three months ended June 30, 2024 |
|
||||||||||||||
|
|
GAAP |
|
Adjustments |
|
Non-GAAP |
|
GAAP |
|
Adjustments |
|
Non-GAAP |
|
||||||
Revenue |
|
$ |
8,507 |
|
$ |
(309) |
|
$ |
8,198 |
|
$ |
10,429 |
|
$ |
(2,854) |
|
$ |
7,575 |
|
Cost of Goods Sold |
|
|
1,519 |
|
|
(100) |
|
|
1,419 |
|
|
1,488 |
|
|
(137) |
|
|
1,351 |
|
Gross Margin |
|
|
6,988 |
|
|
(209) |
|
|
6,779 |
|
|
8,941 |
|
|
(2,717) |
|
|
6,224 |
|
Gross Margin % |
|
|
82 |
% |
|
|
|
|
83 |
% |
|
86 |
% |
|
|
|
|
82 |
% |
|
|
Six months ended June 30, 2025 |
|
Six months ended June 30, 2024 |
|
||||||||||||||
|
|
GAAP |
|
Adjustments |
|
Non-GAAP |
|
GAAP |
|
Adjustments |
|
Non-GAAP |
|
||||||
Revenue |
$ |
18,897 |
$ |
(2,456) |
$ |
16,441 |
$ |
21,770 |
$ |
(6,008) |
$ |
15,762 |
|
||||||
Cost of Goods Sold |
|
|
3,016 |
|
|
(165) |
|
|
2,851 |
|
|
2,891 |
|
|
(137) |
|
|
2,754 |
|
Gross Margin |
|
|
15,881 |
|
|
(2,291) |
|
|
13,590 |
|
|
18,879 |
|
|
(5,871) |
|
|
13,008 |
|
Gross Margin % |
|
|
84 |
% |
|
|
|
|
83 |
% |
|
87 |
% |
|
|
|
|
83 |
% |
(1) |
Adjustments include the exclusion of SPL program related revenue from Revenue, and the exclusion of reserves for excess and obsolete inventory from Cost of Goods Sold. |
10
|
are registered trademarks of MaxCyte, Inc. in the U.S.A. Driving the Next Generation of Cell-Based Therapies MaxCyte Corporate Presentation NASDAQ: MXCT August 2025 © 2025 MaxCyte, Inc. All Rights Reserved |
|
Disclaimer 2 © 2025 MaxCyte, Inc. All Rights Reserved The content of this document (the “Presentation”) has not been approved by an authorized person within the meaning of the Financial Services and Markets Act 2000 (“FSMA”), as amended. Reliance on this document for the purpose of engaging in any investment activity may expose an individual or organization to a significant risk of losing all of their investment. If you are in any doubt about the investment to which this Presentation relates, you should consult a person authorized by the Financial Conduct Authority who specializes in advising on securities of the kind described in this Presentation or your stockbroker, bank manager, solicitor, accountant or other financial adviser. This Presentation has been issued by MaxCyte Inc (the “Company”) and does not constitute or form part of, and should not be construed as, an offer or invitation to sell or issue or any solicitation of any offer to purchase or subscribe for any securities in the Company in any jurisdiction. Neither this Presentation, nor any part of it nor anything contained or referred to in it, nor the fact of its distribution, should form the basis of or be relied on in any connection with or act as an inducement in relation to a decision to purchase or subscribe for or enter into any contract or make any other commitment whatsoever in relation to any such securities. This Presentation does not constitute a recommendation regarding the securities of the Company. This Presentation is only addressed to and directed at (i) persons who are outside the United Kingdom, (ii) persons who have professional experience in matters relating to investments falling within Article 19(5) of the Financial Services and Markets Act 2000 (Financial Promotion) Order 2005, as amended (the "Order"), (iii) persons who are high net worth entities falling within Article 49(2)(a) to (d) of the Order, and/or (iv) any other persons to whom this Presentation may otherwise lawfully be communicated without contravention of section 21 of the Financial Services and Markets Act 2000 or to whom it may otherwise lawfully be distributed (all such persons together being referred to as "relevant persons"). This Presentation may not be acted on or relied on by persons who are not relevant persons. Any investment or investment activity to which this Presentation relates is available only to relevant persons. Certain statements in this Presentation are, or may be deemed to be, forward-looking statements within the meaning of the “safe harbor” provisions of the Private Securities Litigation Reform Act of 1995, including but not limited to statements regarding our expected potential future revenue. The words "may," "might," "will," "could," "would," "should," "expect," "plan," "anticipate," "intend," "believe," "expect," "estimate," "seek," "predict," "future," "project," "potential," "continue," "target" and similar words or expressions are intended to identify forward-looking statements, although not all forward-looking statements contain these identifying words. Any forward-looking statements in this Presentation are based on management's current expectations and beliefs and are subject to a number of risks, uncertainties and important factors that may cause actual events or results to differ materially from those expressed or implied by any forward-looking statements contained in this Presentation, including, without limitation, statements regarding the Company's future growth, results of operations, performance, future capital and other expenditures (including the amount, nature and sources of funding thereof), competitive advantages, business prospects and opportunities. These and other risks and uncertainties are described in greater detail in the section entitled "Risk Factors" in our Annual Report on Form 10-K for the year ended December 31, 2023, our quarterly reports for the periods ended March 31, 2024, June 30, 2024, and September 30, 2024, as well as discussions of potential risks, uncertainties, and other important factors in the other filings that we make with the Securities and Exchange Commission from time to time. These documents are available on the Securities and Exchange Commission website and through the Investor Menu, Financials section under "SEC filings" on the Investors page of our website at http://investors.maxcyte.com. No statement in this Presentation is intended to be, or intended to be construed as, a profit forecast or profit estimate or to be interpreted to mean that earnings per Company share for the current or future financial years will necessarily match or exceed the historical earnings per Company share. As a result, no undue reliance should be placed on such statements. Any forward-looking statements represent our views only as of the date of this Presentation and should not be relied upon as representing our views as of any subsequent date. We explicitly disclaim any obligation to update any forward-looking statements, whether as a result of new information, future events or otherwise. No representations or warranties (expressed or implied) are made about the accuracy of any such forward-looking statements. This Presentation also contains Non-GAAP Gross Margin, which we define as Gross Margin when excluding SPL program related revenue and reserves for excess and obsolete inventory. The Company believes that the use of Non-GAAP Gross Margin provides an additional tool to investors because it provides consistency and comparability with past financial performance, as Non-GAAP Gross Margin excludes non-core revenues and inventory reserves, which can vary significantly between periods and thus affect comparability. Management does not consider these Non-GAAP financial measures in isolation or as an alternative to financial measures determined in accordance with GAAP. The principal limitation of these Non-GAAP financial measures is that they exclude significant revenues and expenses that are required by GAAP to be recorded in the Company’s financial statements. Non-GAAP measures should be considered in addition to results prepared in accordance with GAAP, but should not be considered a substitute for, or superior to, GAAP results. A reconciliation table of Gross Margin, the most comparable GAAP financial measure, to Non-GAAP Gross Margin is included in the appendix of this release. |
|
MaxCyte at a Glance 3 © 2025 MaxCyte, Inc. All Rights Reserved Our Mission We power the future of cell and gene therapy with innovative, scalable cell engineering solutions that enable our customers to deliver advanced therapies to patients Base-editing (CRISPR), CRISPR, ARCUS, RNA-Based Engineering, TALENS, Zinc Finger Nucleases (ZFNs) 19 Clinical and Commercial Therapies Supported 2024 Revenue • Genetic diseases, solid tumors, infectious disease, Hematological • Malignancies, autoimmune disease 31 SPL Customers $165M Cash & Cash Equivalents1 $38.6M 2024 Non-GAAP Adjusted Gross Margins 84% 2 1. As of June 30, 2025 2. Excluding SPL Program-related revenue and reserves for excess and obsolete inventory. See appendix for reconciliation to GAAP gross margins |
|
Cell and Gene Therapy Development 4 © 2025 MaxCyte, Inc. All Rights Reserved Cell Engineering (Electroporation) Cell Proliferation In-Vivo Ex-Vivo Viral/Non-Viral Vector for delivery to Specific Organ Tissue The engineering of cells to develop therapies addressing a host of human diseases with unmet medical needs Cells Collected from Universal Donor or Patient Personalized Therapy Cryopreservation Patient Cell & Gene Therapy is one of the fastest growing and most promising treatment modalities ~1,950 active clinical trials focused on as of Dec 2024* Aggregate of $15.2B raised in 2024* Genetic diseases, solid tumors, infectious disease, hematological, and autoimmune 44 approved cell and gene therapies** *Alliance for Regenerative Medicine (“ARM”) as of Dec 2024 **FDA approved Cellular and Gene Therapy Products |
|
Addressing the Challenges of Cell & Gene Therapy Development 5 © 2025 MaxCyte, Inc. All Rights Reserved Next-generation cell therapy programs have become increasingly complex requiring multiple edits Regulatory risk increases with new unknowns (donor cells, next-gen approaches, new indications) Vein-to-vein manufacturing times are high; optimizations needed to deliver medicines to patients faster Lack of industry standard for cell engineering process development causes costly and inconsistent manufacturing runs Many steps in the cell engineering process with lack of support or safety assessments before regulatory review |
|
Large Opportunity in Ex-Vivo Cell and Gene Therapy 6 © 2025 MaxCyte, Inc. All Rights Reserved MaxCyte # of Potential SPLs Research & Discovery Pre-Clinical Clinical Commercial 124 Programs 82 Non-Viral Programs (66%) 383 Programs 193 Non-Viral Programs (50%) 249 Programs 84 Non-Viral Programs (37%) 10 Programs 1 Non-Viral Program (10%) Ex-Vivo Cell & Gene Therapy TAM 201 Ex-Vivo Cell & Gene Therapy Biotechs 83 Non-Viral Ex-Vivo Cell & Gene Therapy Biotechs Gene Editing Tools: • ARCUS • Base-editing (CRISPR) • Prime-editing (CRISPR) • CRISPR • RNA-Based Engineering • Transposon • TALENS • Zinc Finger Nucleases (ZFNs) Source: MaxCyte Company Estimates for U.S. and EU Markets Programs with undisclosed vector are assumed to be Viral and Non-Viral at the market concentration ratio of 53% to 47%, respectively |
|
The Expert Platform Enabling Non-Viral Cell Engineering 7 © 2025 MaxCyte, Inc. All Rights Reserved Full scale RUO Small/mid-scale RUO Large Scale RUO/cGMP Full scale RUO/cGMP 75 thousand to 700 million cells 75 thousand to 20 billion cells 5 billion to 200 billion cells 75 thousand to 20 billion cells High Performance • >90% transfection efficiencies (depending on cell type and molecule) • >90% cell viabilities • Computer-controlled system for reproducible results Flexibility • Single, fully-defined, animal component-free electroporation buffer for all cell types • Pre-loaded library of validated, cell-specific protocols Scalability – Ability to Transfect • 75,000 to 7 million cells in seconds • Up to 20 billion cells in less than 30 minutes • And up to 200 billion cells in less than 30 minutes with the high scale VLx High Quality • Sterile, single-use processing assemblies (PAs) • Closed, cGMP-compliant, ISO-certified, and CE marked instruments • Supported by US FDA Master File and global equivalents Key Applications: Ex-Vivo Engineered Cell Therapies Customer Base: Leading global cell therapy developers and academic translational centers Additional Electroporation Applications in Drug Discovery Viral Vector Production – Transfect adherent or suspension cells to produce a variety of viral vectors. Cell Based Assays – Produce assay-ready cells faster with scalable electroporation. Gene Editing – Navigate the complexities of genome engineering with highly efficient delivery. Antibody & Protein Production – Accelerate biotherapeutic development with transient expression for gram-scale protein production. Vaccine Development – Innovate vaccine research with our adaptable platform for production of recombinant proteins, virus-like particles and more. |
|
GMP: 25µL – 100mL on 21 CFR Part 11 Compliant MaxCyte’s Solutions Span Cell & Gene Engineering 8 © 2025 MaxCyte, Inc. All Rights Reserved Industry-leading, scalable Expert Electroporation Platform and best-in-class customer support Commercial Strategic platform license for clinical & commercial manufacturing IND-enabling lease Discovery Process Development IND-enabling activities IND-enabling study / Clinical IND filing BLA filing Instrument purchase & research scale Instrument purchase & full scale with flow EP RUO RUO GMP GMP Screening Validation Lead ID Concept Discovery Optimization Verification RUO: 25µL – 3.5mL on RUO: 25µL – 100mL on Strategic platform license for large allogeneic manufacturing GMP: 25µL – 1L on 21 CFR Part 11 Compliant GMP |
|
MaxCyte’s Flow Electroporation® technology integrates efficiently within a closed cGMP cell therapy workflow 9 © 2025 MaxCyte, Inc. All Rights Reserved Cell Isolation & Expansion CCBE Electroporation Cell Expansion Cryopreservation Add loading agent (mRNA, pDNA, RNP…) and Electroporate Process cells on different platforms Wash media and exchange from different platforms to MaxCyte Buffer Infusion and cryopreservation Seamlessly scale from initial cell therapy concept to commercialization • Leverages the reversible permeability of the cell membrane in response to an electric charge • Universally delivers molecules, such as nucleic acids, gene-editing tools and proteins, into cells • Agnostic to cell type, approach (auto/allo) and/or gene manipulation technology • Supported by a robust intellectual property portfolio (200+ patents granted in US and foreign jurisdictions and 100+ patents pending worldwide) • Enables customers to use a single platform from concept through to the clinic in a GMP environment • >100 protocols optimized through 25 years of research by experts in biophysics, biochemistry and cell biology |
|
Development of Ex Vivo Cell Therapies Requires Highly Specialized Engineering Tools and Assays 10 © 2025 MaxCyte, Inc. All Rights Reserved Lentivirus Adeno-associated virus Lipid nanoparticles Electroporation Engineering Tools Delivery Technologies CRISPR/Cas gene editing Transposase integration mRNA transient expression Stable DNA transduction Engineered Cell Therapy Starting Cell Material Post-engineering analyses: • On-target editing confirmation • Off-target editing risk assessment • Cell functional assays • Cell phenotype characterization Engineering Strategies Pre-engineering analyses: • Cell health determination • Cell purity characterization • Cell identity confirmation ✓ Single alteration vs. multiple alterations ✓ Sequential engineering vs. simultaneous engineering ✓ Integrating vs. non-integrating approaches Developing engineering ex vivo cell therapies is highly complex |
|
MaxCyte’s Solutions are Uniquely Positioned to Support Cell Therapy Development 11 © 2025 MaxCyte, Inc. All Rights Reserved Flow Electroporation technology facilitates multiplex and sequential engineering without the payload and capacity limitations of viral approaches 33+1 Field Application Scientists support our customers in their development process Expert platform provides industry leading transfection efficiency & cell viability at high scale in 30 minutes or less, enabling manufacturers to quickly scale up production Regulatory Support Superior Results Complex Engineering Optimization Scientific Support FDA Master File can be referenced in regulatory filings to accelerate and de-risk regulatory review MaxCyte technology allows plug and play processes with rapid optimization delivering reproducible outcomes and the ability to seamlessly scale up from pre-IND to the clinic and commercialization 1. As of December 31, 2024 |
|
MaxCyte’s Platform Generates Recurring Revenue in Pre-Clinical, Clinical, and Commercial 12 © 2025 MaxCyte, Inc. All Rights Reserved Razor/Razor Blade Economics Full scale RUO Preclinical and Academic Revenue Model Instrument Sale Clinical and Commercial Revenue Model Annual License Fee Razor/Razor Blade Economics + Share of Therapeutic Economics Clinical Milestones and Commercial Royalties/Sales Based Payments Single-use Disposables (PAs) Full scale GMP Single-use Disposables (PAs) + + + MaxCyte captures unique economic participation in customers success as a result of its proven technology and differentiated technical, scientific, and regulatory support |
|
MaxCyte has an Active Portfolio of SPLs 13 © 2025 MaxCyte, Inc. All Rights Reserved 1 Commercial Program2 31 SPL Agreements2 18 Programs are currently in clinical development2 Cleared INDs or Equivalent Durable revenue is supported by 14 SPL clients with 18 active clinical programs, and 1 commercial program Sana Biotechnology Beam Therapeutics Lyell Immunopharma cGMP Compatible Platform FDA Master File and Technical Files Experienced FAS and sales support Leading know-how and engineering process improvement 18 Active Clinical Programs Represents ~$210M of precommercial milestone potential12 1. Inclusive of ~$10 million of milestones already received by MaxCyte 2. Updated as of August 6, 2025 14 SPLs with Active Clinical Trials2 SPL with active clinical trial |
|
Typical MaxCyte SPL Economics 14 © 2025 MaxCyte, Inc. All Rights Reserved Early Clinical: (Phase 1/2) Years 1-3 • Mid 6-figure up to low 7-figure milestones • 1-3+ instruments + disposables Mid-late Clinical: (Phase 2/3) Years 3-5+ • 7-figure milestone • Increasing instrument and disposables usage Approval: Year 5+ • Multiple 7-figure milestones based on geographic region (e.g. US and Europe) Commercial Phase • Royalty and/or sales-based payments • Annual instrument fees and disposable sales Instruments and Processing Assemblies Milestones Royalties & Sales-Based Payments Pre-commercial milestones in early clinical, mid-late clinical and product approval Significant development milestones and high-value participation in future commercial success of partners Recurring revenues from lease of instruments and sales of single-use disposables Royalites and Sales-based payments upon partner’s product commercialization |
|
Differentiated Commercial Relationships Expand Sales Funnel 15 © 2025 MaxCyte, Inc. All Rights Reserved Highly Technical Employees Field Application Scientists (FAS) and Commercial Team Unparalleled scientific support to customers Customer relationships at early stages of cell & gene therapy development Signed SPL *Updated as of December 31, 2024 MaxCyte has a team of 33+ highly trained FAS* Global teams providing scientific, technical, and regulatory expertise FAS works with prospective customers to optimize and implement cell engineering methods, processes, and applications MaxCyte grows its sales funnel by leading with scientific, technical, and regulatory expertise 64 Advanced Degrees and 23 PhDs* Support academic and translational institutions, biotech companies, and pharma companies in discovery and pre-clinical |
|
16 © 2025 MaxCyte, Inc. All Rights Reserved As of August 2025 / Includes with SPL Programs with multiple Clinical Trials for different indications Allogeneic Autologous Cell Approach Phase 1 Phase 1/2 Pivotal Commercial Clinical Phase HSCs Other cell types T-cells T-cells Nula-Cel (Kamau Therapeutics) CB010 (NHL) (Caribou Biosciences) Azer-Cel (NHL) (Imugene) Azer-Cel (AID) (TG Therapeutics) KSQ-001EX (KSQ Therapeutics) KSQ-004EX (KSQ Therapeutics) VIPER-101 (Vittoria Biotherapeutics) Other cell types CASGEVYTM for SCD and B-thal (Vertex Pharmaceuticals) CTX112 (B-cell malignancies) (CRISPR Therapeutics) CTX131 (Solid Tumors) (CRISPR Therapeutics) CTX131 (Hematologic Malignancies) (CRISPR Therapeutics) CTX112 (AID) (CRISPR Therapeutics) Indications in Active MaxCyte-Enabled Clinical Trials Genetic Diseases Beta-Thalassemia Sickle Cell Disease Hemophilia B Chronic Granulomatous Disease (CGD) Solid Tumors Non-small Cell Lung Cancer Head and Neck Cancer Glioblastoma Renal Cell Carcinoma Melanoma Other Solid Tumors Hematological Malignancies Acute Lymphoblastic Leukemia Acute Myeloid Leukemia Chronic Lymphocytic Leukemia Multiple Myeloma Non-Hodgkin Lymphoma T Cell Lymphoma Autoimmune Disease Lupus Nephritis ANCA-associated Vasculitis Multiple Sclerosis Type 1 Diabetes Other autoimmune diseases SPL Portfolio: 22 Active Clinical Trials WU-CART-007 (Wugen) |
|
SPL Case Study: CASGEVY® 17 © 2025 MaxCyte, Inc. All Rights Reserved CASGEVY® for Sickle Cell Disease (SCD) and for Transfusion-Dependent Beta-Thalassemia (TDT) (2023 and 2024) 2013 – MaxCyte supports Inception Genomics (Changed name to CRISPR Therapeutics AG in 2014) • Support for programs in research 2018 – Vertex/CRISPR achieves IND Milestone Sept 28, 2022 – MaxCyte Signs SPL with Vertex to advance Exa-cel • Vertex obtains non-exclusive clinical and commercial rights to use MaxCyte’s Expert platform Dec 8, 2023 – FDA Approves CASGEVY® (for treatment of SCD) 2021 – Vertex initiated Pivotal Trial for CASGEVY® Jan 16, 2024 – FDA Approves CASGEVY® (for treatment of TDT) Feb 12, 2024 – European Commission Approves CASGEVY® (for treatment of SCD and TDT) Nov 15, 2023 – UK MHRA Approves CASGEVY® (for treatment of SCD and TDT) CASGEVY® Jan 9, 2024 – SFDA Approves CASGEVY® (for treatment of SCD and TDT) |
|
MaxCyte Supports the Future of Cell & Gene Therapies 18 © 2025 MaxCyte, Inc. All Rights Reserved WAVE 1 1 Approved Product WAVE 2 5 Product Candidates WAVE 3 13 Product Candidates WAVE 4 19 Product Candidates Vertex/ CRISPR CASGEVY® Approved 2023 US FDA, European Commission & Additional Regulatory Bodies Launch Potential: 2027 – 2028 5 products set to enter pivotal studies in next 6 to 18 months Launch Potential: 2028 + 13 products currently in Phase 1 Launch Potential: 2032 + 19 products in preclinical development Source: Evaluate Pharma, Broker Estimates and MaxCyte Internal Estimates as of August 2025 MaxCyte’s supports a diverse portfolio of product candidates with significant development milestone and commercial royalty potential |
|
MaxCyte’s Roadmap to Becoming a Premier Cell Engineering Solutions Providers 19 © 2025 MaxCyte, Inc. All Rights Reserved Electroporation technology provider Comprehensive cell engineering solutions Gene Editing Tools Over $1.25b market • Key markets addressed: in vivo and ex vivo cell therapy • Other key markets addressed: Agbio, bioprocessing, research and discovery tools Genetic Payloads (i.e. gene insertion/expression) Over $6.0b market • Key markets addressed: in vivo and ex vivo cell therapy • Other key markets addressed: vaccines, bioprocessing, research and discovery tools Other Biological Delivery Over $4.0b market • Key markets addressed: in vivo and ex vivo cell therapy • Other key markets addressed: vaccines, bioprocessing, research and discovery tools Cell engineering risk assessment Organic and Inorganic Investment • Product Development • Acquisitions • Licensing Deals • Distribution Deals Source: Internal analysis |
|
Editing Assessment Services Strategy 20 © 2025 MaxCyte, Inc. All Rights Reserved MaxCyte provides ex-vivo and in-vivo developers with best-in-class on-target and off-target risk assessment services Use Cases: candidate guide screening, guide RNA selection Use Cases: Off-target risk assessment, guide RNA selection, IND filings ✓ Highly sensitive ✓ Universal for all editors ✓ Population-scale variant assessment ✓ Multiple orthogonal methods ✓ Variant effect prediction ✓ GLP-grade Guide Screening ✓ Rapid turnaround time ✓ Comprehensive report ✓ Minimize risk from variation at on-target locus Guide RNA Selection ✓ Low-cost per guide ✓ Evaluate multiple guides ✓ Reduce program risk through early profiling and selection Use Cases: Cellular Editing Assessment, IND filings ✓ Sensitive detection methods ✓ Relevant cell types ✓ On- and off-target analysis ✓ Biologic impact assessment ✓ GLP-grade ✓ Increases program likelihood of success ✓ Decreases risk of unexpected costs or program delays ✓ Aligns with most recent FDA guidance for gene edited therapies ✓ Quicker time to clinic and safer therapies Discovery Pre-Clinical Development and IND-Enabling Studies BENEFITS |
|
21 © 2025 MaxCyte, Inc. All Rights Reserved Financial Summary $1.8 $2.1 $3.0 $3.1 $2.6 $2.6 $0.1 $0.2 $0.3 $2.9 2Q24 2Q25 Core Revenue: +8% Growth $8.3 $7.1 $10.3 $14.0 $10.3 $10.3 $0.9 $1.1 $11.5 $6.1 2023 2024 Core Revenue: +9% Growth 1. Excluding SPL Program-related revenue and reserves for excess and obsolete inventory. See appendix for reconciliation to GAAP gross margins Financial Highlights (As of June 30, 2025) 83% Non-GAAP adjusted Gross Margin1 42% SPL Program-Related revenue as a percentage of Core revenue 814 Total Installed Base of Instruments (sold or leased) $165 million Total cash, cash equivalents, and investments Total Annual Revenue (millions) Core Revenue Total Quarterly Revenue (millions) Core Revenue $41.3 $38.6 $10.4 $8.5 |
|
Financial Summary 22 © 2025 MaxCyte, Inc. All Rights Reserved In millions, except percentages 2023 2024 YTD 2025 Total Core Revenue $29.8 $32.5 $16.4 y/y growth (25%) 9% 4% SPL-Program Related Revenue $11.5 $6.1 $2.5 y/y growth 148% (47%) (59%) Total Revenue $41.3 $38.6 $18.9 y/y growth (7%) (6%) (13%) Gross Profit $36.5 $31.5 $15.9 Gross Margin % 89% 82% 84% Non-GAAP Adjusted Gross Margin %1 86% 84% 83% Operating Expenses $84.8 $82.7 $42.4 Net Income (Loss) ($37.9) ($41.1) ($22.7) EBITDA2 ($44.1) ($46.9) ($24.3) Full Year Ended December 31, 1. Excluding SPL Program-related revenue and reserves for excess and obsolete inventory. See appendix for reconciliation to GAAP gross margins 2. See appendix for Unaudited Reconciliation of Net Loss to EBITDA 6 months |
|
Disciplined Management is Committed to Growth Investment and Efficient Spending 23 © 2025 MaxCyte, Inc. All Rights Reserved MaxCyte is well capitalized and funded to achieve profitability with existing capital Alignment of spending and resources to growth areas Organic investment in new products and product enhancements Reduction of annual cash burn excluding one-time and non-cash items Realize operating leverage on existing cost base Inorganic investment to solve critical pain points in Cell & Gene Therapy Healthy balance sheet ~$165M of cash, cash equivalents, and investments1 |
|
All other trademarks are the property of their respective owners. ©2025 MaxCyte, Inc. All rights reserved. For a complete list of MaxCyte trademarks in the United States and other countries, please visit maxcyte.com/trademarks. Thank you! Any questions? ir@maxcyte.com 24 © 2025 MaxCyte, Inc. All Rights Reserved |
|
Appendix – Historical Core Business Disclosure 25 © 2025 MaxCyte, Inc. All Rights Reserved 1Q'21 2Q'21 3Q'21 4Q'21 1Q'22 2Q'22 3Q'22 4Q'22 1Q'23 2Q'23 3Q'23 4Q'23 1Q'24 2Q’24 3Q’24 4Q’24 1Q’25 2Q’25 (in $ thousands) Instrument 1,627 1,417 2,517 2,917 2,728 2,697 2,575 3,705 2,189 2,126 1,672 2,330 1,928 1,762 1,764 1,629 1,444 2,141 PAs 2,449 2,624 2,927 4,309 3,840 4,114 4,350 3,721 2,600 3,293 2,226 2,163 3,432 2,974 3,432 4,169 3,871 3,128 Licenses 2,252 2,386 2,527 2,643 2,726 2,622 2,736 2,813 2,809 2,667 2,444 2,406 2,604 2,610 2,528 2,554 2,531 2,619 Assay service - - - - - - - - - - - - - - - - 142 51 Other 163 177 165 279 290 171 227 331 174 203 258 263 224 229 416 258 255 259 Total Core Revenue 6,491 6,604 8,135 10,148 9,583 9,604 9,889 10,570 7,772 8,289 6,600 7,162 8,188 7,575 8,140 8,610 8,243 8,198 Installed base of instruments (sold or leased) 420 445 472 502 521 546 575 616 633 654 664 683 708 723 739 760 787 814 Core Revenue Generated by SPL Clients as a % of Core Revenue 42% 43% 37% 39% 47% 47% 40% 34% 52% 49% 45% 45% 53% 51% 53% 55% 57% 42% |
|
Appendix – Unaudited Reconciliation of Gross Margin to Non-GAAP Adjusted gross margin 26 © 2025 MaxCyte, Inc. All Rights Reserved 1. Adjustments include the exclusion of SPL program related revenue from Revenue, and the exclusion of reserves for excess and obsolete inventory from Cost of Goods Sold. Unaudited Reconciliation of Gross Margin to Non-GAAP Adjusted gross margin (in thousands, except for percentages) (Unaudited) Three months ended June 30, 2025 Three months ended June 30, 2024 GAAP Adjustments Non-GAAP GAAP Adjustments Non-GAAP Revenue $ 8,507 $ (309 $ 8,198 $ 10,429 $ (2,854) $ 7,575 Cost of Goods Sold 1,519 (100) 1,419 1,488 (137) 1,351 Gross Margin 6,988 (209) 6,779 8,941 (2,717) 6,224 Gross Margin % 82% 83% 86% 82% Six months ended June 30, 2025 Six months ended June 30, 2024 GAAP Adjustments Non-GAAP GAAP Adjustments Non-GAAP Revenue $ 18,897 $ (2,455) $ 16,442 $ 21,770 $ (6,008) $ 15,762 Cost of Goods Sold 3,016 (165) 2,851 2,891 (137) 2,754 Gross Margin 15,881 (2,290) 13,591 18,879 (5,871) 13,008 Gross Margin % 84% 83% 87% 83% |
|
Appendix – Unaudited Reconciliation of Net Loss to EBITDA 27 © 2025 MaxCyte, Inc. All Rights Reserved Unaudited Reconciliation of Net Loss to EBITDA (in thousands) (Unaudited) Three Months Ended Six Months Ended June 30, June 30, 2025 2024 2025 2024 (in thousands) Net loss $ (12,357) $ (9,375) $ (22,618) $ (18,901) Depreciation and amortization expense 1,100 1,081 2,196 2,192 Interest income (1,870) (2,593) (3,904) (5,342) Income taxes — — — — EBITDA $ (13,127) $ (10,887) $ (24,326) $ (22,051) |
