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UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
WASHINGTON, D.C. 20549

 

FORM 8-K

 

CURRENT REPORT

Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934

Date of Report (Date of earliest event reported): April 01, 2026

 

 

Perspective Therapeutics, Inc.

(Exact name of Registrant as Specified in Its Charter)

 

 

Delaware

001-33407

41-1458152

(State or Other Jurisdiction
of Incorporation)

(Commission File Number)

(IRS Employer
Identification No.)

 

 

 

 

 

c/o Perspective Therapeutics, Inc.

2401 Elliott Avenue

Suite 320

 

Seattle, Washington

 

98121

(Address of Principal Executive Offices)

 

(Zip Code)

 

Registrant’s Telephone Number, Including Area Code: (206) 676-0900

 

 

(Former Name or Former Address, if Changed Since Last Report)

 

Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions:

☐Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)
☐Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)
☐Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))
☐Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))

Securities registered pursuant to Section 12(b) of the Act:


Title of each class

 

Trading
Symbol(s)

 


Name of each exchange on which registered

Common Stock, $0.001 par value

 

CATX

 

NYSE American LLC

Indicate by check mark whether the registrant is an emerging growth company as defined in Rule 405 of the Securities Act of 1933 (§ 230.405 of this chapter) or Rule 12b-2 of the Securities Exchange Act of 1934 (§ 240.12b-2 of this chapter).

Emerging growth company ☐

If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act. ☐

 


Item 8.01 Other Events.

On April 1, 2026, Perspective Therapeutics, Inc. updated its corporate presentation. A copy of the presentation is filed as Exhibit 99.1 to this Current Report on Form 8-K and is incorporated by reference into this Item 8.01.

Item 9.01 Financial Statements and Exhibits.

(d) Exhibits

 

Exhibit No.

 

Description

99.1

 

Corporate Presentation.

104

 

Cover Page Interactive Data File (embedded within the Inline XBRL document).

 


SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.

 

 

 

PERSPECTIVE THERAPEUTICS, INC.

 

 

 

 

Date:

April 1, 2026

By:

/s/ Joel Sendek

 

 

 

Joel Sendek
Chief Financial Officer

 


EX-99.1 2 catx-ex99_1.htm EX-99.1

Slide 1

Redefining Oncology Treatment with Next-Generation Radiopharmaceuticals


Slide 2

 


Slide 3

Why Radiotherapy, Why Perspective: Realizing the Untapped Value Across Oncology


Slide 4

Rapidly Advancing Best-in-Class Next Generation Radiopharmaceuticals


Slide 5

Proprietary Radioligand Platform Optimizes Therapeutic Index


Slide 6

Proprietary Pb-Based Chelator Designed for Broader and Safer Use


Slide 7

Lead-212: Optimal Isotope with Advantages Over Beta and Other Alpha Emitters


Slide 8

Imaging Optimizes Targeted Delivery to Tumor


Slide 9

 


Slide 10

Solid Tumors are an Attractive Market for Radiopharmaceuticals


Slide 11

End-to-End Manufacturing with Clinical Supply Secured and Commercial Scale Underway


Slide 12

Advancing a Diverse Wholly Owned 212Pb-Based Oncology Portfolio


Slide 13

SSTR2+ Neuroendocrine Tumors is a Large, Growing Market with Significant Unmet Need


Slide 14

VMT-⍺-NET: Potential First-in-Class 212Pb-Radioligand Therapy Targeting SSTR2


Slide 15

Ongoing Phase 1/2a to Establish Broad Therapeutic Window For VMT-⍺-NET in NETs


Slide 16

Compelling Anti-tumor Activity with Sustained or Deepening Responses


Slide 17

VMT-⍺-NET: Durable Disease Control Across All Doses


Slide 18

Best-in-class Safety Profile1


Slide 19

VMT-α-NET’s Compelling Profile Supports Potential Registration Study at Current Dose Level


Slide 20

Checkpoint Inhibitors Transformed Care of Melanoma but Leave Many Patients Behind


Slide 21

VMT01: Potential First-in-Class 212Pb Therapy Targeting MC1R for Melanoma


Slide 22

Ongoing Phase 1/2a Open-Label Trial For VMT01 in Melanoma


Slide 23

Preliminary Anti-tumor Activity Observed at Lower Dose of VMT01


Slide 24

Treatment Emergent Adverse Events (All Grades, Occurring in ≥ 2 Patients)


Slide 25

VMT01 is Well-tolerated with Initial Anti-tumor Activity Supporting Further Development


Slide 26

FAP-ɑ is an Attractive Cancer Target with Broad Solid Tumor Potential


Slide 27

PSV359: Potential First-in-Class 212Pb Therapy Targeting FAP-ɑ for Solid Tumors


Slide 28

Ongoing Open-label Phase 1/2a Trial For PSV359 in Advanced Solid Tumors


Slide 29

PSV359 has Improved Tumor Retention, Highlighting its Potential as a Therapeutic Agent


Slide 30

Strong IP Portfolio Covering All Aspects of Radiopharmaceutical Value Chain


Slide 31

 


Slide 32

Phase 1/2 Data Expected Across All 3 Clinical Programs in 2026


Slide 33

 


Slide 34

Abbreviations


Slide 35

APPENDIX


Slide 36

 


Slide 37

NETs Trials


Slide 38

VMT-⍺-NET: Baseline Patient Characteristics in ASCO-GI 2026 Data Analysis


Slide 39

Patient Exposure and Follow-up with [212Pb]VMT-α-NET in ASCO-GI 2026 Data Analysis


Slide 40

VMT-⍺-NET: Durable Disease Control Across All Doses


Slide 41

VMT-⍺-NET: Signal of Sustained Anti-tumor Activity


Slide 42

Patient with Confirmed PR After [212Pb]VMT-α-NET Treatment


Slide 43

Blood Creatinine During Follow-up for All Patients Treated (n=56)


Slide 44

Refractory Metastatic Melanoma Trials


Slide 45

ICI Combo Rationale: Strong Synergy with [212Pb]VMT01 in Melanoma


Slide 46

 


Slide 47

Daily production at regional sites ensures supply of ready-to-administer product


Slide 48

 


Slide 49

Perspective’s proprietary chelator has been optimized for lead-based RPTs


Slide 50

Construct designed for better clinical outcome


Slide 51

 


Slide 52

 


Slide 53