UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 8-K
CURRENT REPORT
Pursuant to Section 13 or 15(d) of the
Securities Exchange Act of 1934
Date of report (Date of earliest event reported): August 20, 2025
Silexion Therapeutics Corp
(Exact name of registrant as specified in its charter)
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Cayman Islands
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001-42253
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N/A |
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(State or other jurisdiction
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(Commission File Number)
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(I.R.S. Employer
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of incorporation)
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Identification No.)
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12 Abba Hillel Road Ramat-Gan, Israel |
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5250606
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(Address of principal executive offices)
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(Zip Code)
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Check the appropriate box below if the Form 8-K is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions:
| ☐ |
Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425) |
| ☐ |
Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12) |
| ☐ |
Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b)) |
| ☐ |
Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c)) |
Securities registered pursuant to Section 12(b) of the Act:
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Title of each class
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Trading Symbol(s)
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Name of each exchange on which registered
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| Ordinary Shares, par value $0.0135 per share |
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SLXN |
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The Nasdaq Stock Market LLC |
| Warrants exercisable for Ordinary Shares at an exercise price of $1,552.50 per share |
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SLXNW |
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The Nasdaq Stock Market LLC |
Indicate by check mark whether the registrant is an emerging growth company as defined in Rule 405 of the Securities Act of 1933 (§230.405 of this chapter) or Rule 12b-2 of the Securities Exchange Act of 1934 (§240.12b-2 of this chapter).
Emerging growth company ☒
If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act. ☐
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Item 8.01
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Other Events.
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Item 9.01
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Financial Statements and Exhibits.
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101.INS*
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Inline XBRL Instance Document.
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||
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101.SCH*
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Inline XBRL Taxonomy Extension Schema Document.
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||
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101.CAL*
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Inline XBRL Taxonomy Extension Calculation Linkbase Document.
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||
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101.DEF*
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Inline XBRL Taxonomy Extension Definition Linkbase Document.
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||
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101.LAB*
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Inline XBRL Taxonomy Extension Label Linkbase Document.
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||
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101.PRE*
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Inline XBRL Taxonomy Extension Presentation Linkbase Document.
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||
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104*
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Cover Page Interactive Data File (formatted as Inline XBRL and contained in Exhibit 101).
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SILEXION THERAPEUTICS CORP
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Date: August 20, 2025
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By:
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/s/ Ilan Hadar |
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Name:
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Ilan Hadar
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Title:
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Chief Executive Officer
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Page
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|
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Report of Independent Registered Public Accounting Firm (PCAOB name: Kesselman & Kesselman C.P.As and PCAOB ID: 1309)
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F-2
|
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CONSOLIDATED FINANCIAL STATEMENTS:
|
|
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F-3 - F-4
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|
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F-5
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F-6
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|
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F-7 - F-8
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F-9 - F-36
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/s/Kesselman & Kesselman
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Certified Public Accountants (lsr.)
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A member firm of PricewaterhouseCoopers International Limited
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Tel-Aviv, Israel
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March 18, 2025, except for the effects of the reverse share split effected July 28, 2025 as discussed in note 1h, as to which the date is August 20, 2025
We have served as the Company's auditor since 2023.
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Kesselman & Kesselman, 146 Derech Menachem Begin St. Tel-Aviv 6492103, Israel, P.O Box 7187 Tel-Aviv 6107120, Telephone: +972 -3- 7954555, Fax:+972 -3- 7954556, www.pwc.com/il
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December 31
|
||||||||
|
2024
|
2023
|
|||||||
|
Assets
|
||||||||
|
CURRENT ASSETS:
|
||||||||
|
Cash and cash equivalents
|
$
|
1,187
|
$
|
4,595
|
||||
|
Restricted cash
|
35
|
25
|
||||||
|
Prepaid expenses
|
966
|
335
|
||||||
|
Other current assets
|
62
|
24
|
||||||
|
TOTAL CURRENT ASSETS
|
2,250
|
4,979
|
||||||
|
NON-CURRENT ASSETS:
|
||||||||
|
Restricted cash
|
48
|
25
|
||||||
|
Long-term deposit
|
5
|
5
|
||||||
|
Property and equipment, net
|
30
|
49
|
||||||
|
Operating lease right-of-use asset
|
530
|
198
|
||||||
|
TOTAL NON-CURRENT ASSETS
|
613
|
277
|
||||||
|
TOTAL ASSETS
|
$
|
2,863
|
$
|
5,256
|
||||
|
December 31
|
||||||||
|
2024
|
2023
|
|||||||
|
Liabilities and redeemable convertible preferred shares, net of capital deficiency
|
||||||||
|
CURRENT LIABILITIES:
|
||||||||
|
Trade payables
|
$
|
929
|
$
|
319
|
||||
|
Current maturities of operating lease liability
|
158
|
112
|
||||||
|
Warrants to preferred shares (including $0 and $186 due to related party, as of December 31, 2024 and December 31, 2023, respectively)
|
-
|
200
|
||||||
|
Employee related obligations
|
642
|
207
|
||||||
|
Accrued expenses and other accounts payable
|
788
|
1,358
|
||||||
|
Private warrants to purchase ordinary shares (including $1 and $0 due to related party, as of December 31, 2024 and December 31, 2023, respectively)
|
2
|
-
|
||||||
|
Underwriters Promissory Note
|
1,004
|
-
|
||||||
|
TOTAL CURRENT LIABILITIES
|
3,523
|
2,196
|
||||||
|
NON-CURRENT LIABILITIES:
|
||||||||
|
Long-term operating lease liability
|
368
|
59
|
||||||
|
Related Party Promissory Note
|
2,961
|
-
|
||||||
|
TOTAL NON-CURRENT LIABILITIES
|
$
|
3,329
|
$
|
59
|
||||
|
TOTAL LIABILITIES
|
$
|
6,852
|
$
|
2,255
|
||||
|
COMMITMENTS AND CONTINGENT LIABILITIES (Note 7)
|
||||||||
|
REDEEMABLE CONVERTIBLE PREFERRED SHARES AND NON-CONTROLLING INTERESTS:
|
||||||||
|
Convertible Series A Preferred Shares (NIS 1.35 par value, 0 and 3,778 shares authorized as of December 31, 2024 and 2023, 0 and 2,875 shares issued and outstanding as of December 31, 2024 and 2023);
|
||||||||
|
Convertible Series A-1 Preferred Shares (NIS 1.35 par value per share, 0 and 889 shares authorized as of December 31, 2024 and 2023, 0 and 676 shares issued and outstanding as of December 31, 2024 and 2023);
|
||||||||
|
Convertible Series A-2 Preferred Shares (NIS 1.35 par value per share, 0 and 1,482 shares authorized as of December 31, 2024 and 2023, 0 and 337 shares issued and outstanding as of December 31, 2024 and 2023);
|
||||||||
|
Convertible Series A-3 Preferred Shares (NIS 1.35 par value per share, 0 and 593 shares authorized as of December 31, 2024 and 2023, 0 and 470 shares issued and outstanding as of December 31, 2024 and 2023);
|
||||||||
|
Convertible Series A-4 Preferred Shares (NIS 1.35 par value per share 0 and 6,038 and shares authorized as of December 31, 2024 and 2023, respectively 0 and 161** shares issued and outstanding as of December 31, 2024 and 2023, respectively);
|
||||||||
|
TOTAL REDEEMABLE CONVERTIBLE PREFERRED SHARES
|
-
|
15,057
|
||||||
|
CONTINGENTLY REDEEMABLE NON-CONTROLLING INTERESTS
|
-
|
3,420
|
||||||
|
TOTAL REDEEMABLE CONVERTIBLE PREFERRED SHARES AND CONTINGENTLY REDEEMABLE NON-CONTROLLING INTERESTS
|
$
|
-
|
$
|
18,477
|
||||
|
CAPITAL DEFICIENCY:
|
||||||||
|
Ordinary shares ($0.0135 par value per share, 1,481,482 shares authorized as of December 31, 2024 and 2023; 123,290**** and 6,516 shares issued and outstanding as of December 31, 2024 and 2023, respectively)
|
2
|
*
|
||||||
|
Additional paid-in capital
|
39,263
|
11,335
|
||||||
|
Accumulated deficit
|
(43,254
|
)
|
(26,811
|
)
|
||||
|
TOTAL CAPITAL DEFICIENCY
|
$
|
(3,989
|
)
|
$
|
(15,476
|
)
|
||
|
TOTAL REDEEMABLE CONVERTIBLE PREFERRED SHARES AND CONTINGENTLY REDEEMABLE NON-CONTROLLING INTERESTS, NET OF CAPITAL DEFICIENCY
|
$
|
(3,989
|
)
|
$
|
3,001
|
|||
|
TOTAL LIABILITIES, REDEEMABLE CONVERTIBLE
|
||||||||
|
PREFERRED SHARES AND NON-CONTROLLING INTEREST, NET OF CAPITAL DEFICIENCY
|
$
|
2,863
|
$
|
5,256
|
||||
|
Year ended December 31
|
||||||||
|
2024
|
2023
|
|||||||
|
OPERATING EXPENSES:
|
||||||||
|
Research and development (including $1,796 and $69 from related party, for the year ended December 31, 2024 and December 31, 2023, respectively)
|
$
|
5,815
|
$
|
3,708
|
||||
|
General and administrative (including $2,972 and $48 from related party, for the year ended December 31, 2024 and December 31, 2023, respectively)
|
6,756
|
973
|
||||||
|
TOTAL OPERATING EXPENSES
|
12,571
|
4,681
|
||||||
|
OPERATING LOSS
|
12,571
|
4,681
|
||||||
|
Financial expenses (income), net (including $(1,249) and $83 from related party, for the year ended December 31, 2024 and December 31, 2023, respectively)
|
3,938
|
395
|
||||||
|
LOSS BEFORE INCOME TAX
|
$
|
16,509
|
$
|
5,076
|
||||
|
INCOME TAX
|
10
|
32
|
||||||
|
NET LOSS FOR THE YEAR
|
$
|
16,519
|
$
|
5,108
|
||||
|
Attributable to:
|
||||||||
|
Equity holders of the Company
|
16,443
|
4,942
|
||||||
|
Non-controlling interests
|
76
|
166
|
||||||
|
$
|
16,519
|
$
|
5,108
|
|||||
|
LOSS PER ORDINARY SHARE, BASIC AND DILUTED*
|
$
|
394.94
|
$
|
659.55
|
||||
|
WEIGHTED AVERAGE NUMBER OF ORDINARY SHARES OUTSTANDING USED IN COMPUTATION OF BASIC AND DILUTED LOSS PER SHARE*:
|
41,635
|
7,493
|
|
Redeemable Convertible Preferred Shares
|
Ordinary shares
|
Additional
paid-in Capital |
Accumulated deficit
|
Total capital deficiency
|
Total redeemable convertible preferred shares and contingently redeemable non-controlling interests, net of capital deficiency
|
|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
|
Series A preferred shares
|
Series A-1 preferred shares
|
Series A-2 preferred shares
|
Series A-3 preferred shares
|
Series A-4 preferred shares
|
Contingently redeemable non-controlling
interests
|
|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
|
Shares
|
Amount
|
Shares
|
Amount
|
Shares
|
Amount
|
Shares
|
Amount
|
Shares
|
Amount
|
Amount
|
Shares
|
Amount
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
|
BALANCE AT JANUARY 1, 2023
|
2,875
|
$
|
7,307
|
676
|
$
|
2,392
|
337
|
$
|
2,264
|
470
|
$
|
2,683
|
-
|
-
|
$
|
3,586
|
6,516
|
*
|
$
|
11,204
|
$
|
(21,869
|
)
|
$
|
(10,665
|
)
|
$
|
7,567
|
||||||||||||||||||||||||||||||||||||||||||
|
CHANGES DURING 2023:
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
|
Issuance of Preferred A-4 shares, net of issuance cost, see Note 9(1)
|
161
|
$
|
411
|
1
|
1
|
412
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
|
Share-based compensation
|
130
|
130
|
130
|
|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
|
Net loss
|
(166
|
) |
|
(4,942
|
)
|
(4,942
|
)
|
(5,108
|
)
|
|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
|
BALANCE AT DECEMBER 31, 2023
|
2,875
|
$
|
7,307
|
676
|
$
|
2,392
|
337
|
$
|
2,264
|
470
|
$
|
2,683
|
161
|
$
|
411
|
$
|
3,420
|
6,516
|
* |
$
|
11,335
|
$
|
(26,811
|
)
|
$
|
(15,476
|
)
|
$
|
3,001
|
|||||||||||||||||||||||||||||||||||||||||
|
CHANGES DURING 2024:
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
|
Exercise of pre-funded options
|
919
|
**
|
* |
*
|
*
|
|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
|
Share-based compensation
|
5,242
|
* |
5,862
|
5,862
|
5,862
|
|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
|
Issuance of convertible preferred shares upon net exercise of warrants
|
10
|
-
|
62
|
$
|
334
|
-
|
-
|
334
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
|
Net loss
|
(76
|
) |
|
(16,443
|
)
|
(16,443
|
)
|
(16,519
|
)
|
|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
|
Conversion of convertible preferred shares and noncontrolling interests upon the effectiveness of the SPAC Merger (see Note 1(d))
|
(2,875
|
)
|
$
|
(7,307
|
)
|
(686
|
)
|
$
|
(2,392
|
)
|
(337
|
)
|
$
|
(2,264
|
)
|
(470
|
)
|
$
|
(2,683
|
)
|
(223
|
)
|
$
|
(745
|
)
|
$
|
(3,344
|
) |
|
31,873
|
1 |
18,734
|
18,735
|
-
|
||||||||||||||||||||||||||||||||||||
|
Issuance of ordinary shares upon Transactions (see Note 1(d))
|
27,825
|
* |
*
|
*
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
|
Issuance of ordinary shares for ELOC holders, see Note 3(d)
|
50,915
|
1 |
3,332
|
3,333
|
3,333
|
|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
|
BALANCE AT DECEMBER 31, 2024
|
-,-
|
-,- |
-,- |
-,- |
-,- |
-,- |
-,- |
-,- |
-,- |
-,- |
-,- |
123,290
|
****
|
$ | 2 |
$
|
39,263
|
$
|
(43,254
|
)
|
$
|
(3,989
|
)
|
$
|
(3,989
|
)
|
||||||||||||||||||||||||||||||||||||||||||||
|
Year ended December 31
|
||||||||
|
2024
|
2023
|
|||||||
|
CASH FLOWS FROM OPERATING ACTIVITIES:
|
||||||||
|
Net loss
|
$
|
(16,519
|
)
|
$
|
(5,108
|
)
|
||
|
Adjustments required to reconcile loss to net cash used in operating activities:
|
||||||||
|
Depreciation
|
25
|
45
|
||||||
|
Share-based compensation expenses
|
5,862
|
130
|
||||||
|
Non-cash loss upon entering Transactions
|
4,783
|
-
|
||||||
|
Other non-cash financial expenses (income)
|
(1,051
|
)
|
318
|
|||||
|
Loss )gain( on disposal of property and equipment
|
16
|
(1
|
)
|
|||||
|
Loss from lease termination
|
68
|
-
|
||||||
|
Changes in operating assets and liabilities:
|
||||||||
|
Increase in prepaid expenses
|
(631
|
)
|
(329
|
)
|
||||
|
Decrease (increase) in other current assets
|
(38
|
)
|
18
|
|||||
|
Increase in trade payable
|
610
|
79
|
||||||
|
Net change in operating lease
|
(57
|
)
|
6
|
|||||
|
Increase (decrease) in employee related obligations
|
435
|
(46
|
)
|
|||||
|
Increase (decrease) in accrued expenses and other accounts payable
|
(1,899
|
)
|
359
|
|||||
|
Net cash used in operating activities
|
(8,396
|
)
|
(4,529
|
)
|
||||
|
CASH FLOWS FROM INVESTING ACTIVITIES:
|
||||||||
|
Proceeds from short-term deposit
|
-
|
507
|
||||||
|
Purchase of property and equipment
|
(22
|
)
|
(12
|
)
|
||||
|
Proceeds from sale of property and equipment
|
-
|
78
|
||||||
|
Net cash provided by (used in (investing activities
|
(22
|
)
|
573
|
|||||
|
CASH FLOWS FROM FINANCING ACTIVITIES:
|
||||||||
|
Proceeds from issuance of preferred shares and warrants, net of issuance costs
|
-
|
522
|
||||||
|
Proceeds from exercise of pre-funded options
|
*
|
-
|
||||||
|
Net proceeds from issuance of ordinary shares (ELOC)
|
3,054
|
-
|
||||||
|
Cash received from Transactions upon the effectiveness of the SPAC Merger
|
2,300
|
-
|
||||||
|
Payment of Underwriters Promissory Note
|
(250
|
)
|
-
|
|||||
|
Net cash provided by financing activities
|
5,104
|
522
|
||||||
|
DECREASE IN CASH AND CASH EQUIVALENTS AND RESTRICTED CASH
|
(3,314
|
)
|
(3,434
|
)
|
||||
|
EXCHANGE RATE DIFFERENCES ON CASH AND CASH EQUIVALENTS AND RESTRICTED CASH
|
(61
|
)
|
(230
|
)
|
||||
|
BALANCE OF CASH, CASH EQUIVALENTS AND RESTRICTED CASH AT BEGINNING OF YEAR
|
4,645
|
8,309
|
||||||
|
BALANCE OF CASH, CASH EQUIVALENTS AND RESTRICTED CASH AT END OF YEAR
|
$
|
1,270
|
$
|
4,645
|
||||
|
Year ended December 31
|
||||||||
|
2024
|
2023
|
|||||||
|
Appendix A –
|
||||||||
|
RECONCILIATION OF CASH, CASH EQUIVALENTS AND RESTRICTED CASH REPORTED IN THE CONSOLIDATED BALANCE SHEETS:
|
||||||||
|
Cash and cash equivalents
|
1,187
|
4,595
|
||||||
|
Restricted cash
|
83
|
50
|
||||||
|
TOTAL CASH, CASH EQUIVALENTS AND RESTRICTED CASH SHOWN IN STATEMENT OF CASH FLOWS
|
$
|
1,270
|
$
|
4,645
|
||||
|
Appendix B - SUPPLEMENTARY INFORMATION:
|
||||||||
|
SUPPLEMENTARY INFORMATION ON INVESTING AND FINANCING ACTIVITIES NOT INVOLVING CASH FLOWS:
|
||||||||
|
Derecognition of right-of-use asset recognized and lease liability as a result of operating lease termination
|
$
|
(89
|
)
|
-
|
||||
|
Conversion of preferred shares to ordinary shares
|
$
|
15,391
|
-
|
|||||
|
Conversion of warrants to preferred shares on a cashless basis
|
$
|
334
|
-
|
|||||
|
Conversion of non-controlling interests to New Silexion ordinary shares
|
$
|
3,344
|
-
|
|||||
|
Shares issued for ELOC financing liability
|
$
|
312
|
-
|
|||||
|
Right-of-use asset recognized with a corresponding lease liability
|
$
|
506
|
-
|
|||||
|
SUPPLEMENTAL DISCLOSURES OF CASH FLOW INFORMATION:
|
||||||||
|
Interest paid
|
$
|
27
|
-
|
|||||
|
Interest received
|
$
|
28
|
$
|
153
|
||||
| a. |
Silexion Therapeutics Corp (“New Silexion”) (hereinafter - the “Company” or the “Combined Company”) is a recently formed entity that was formed for the purpose of effecting the Transactions (as defined below). Following the closing of the Transactions on August 15, 2024 (the “Closing”), New Silexion now serves as a publicly-traded holding company that has two primary wholly-owned subsidiaries —Moringa Acquisition Corp (“Moringa” or the “SPAC”), a Cayman Islands exempted company, and Silexion Therapeutics Ltd. (formerly known as Silenseed Ltd.) (“Silexion”), an Israeli limited company.
|
| b. |
Financial Information Presented:
|
| c. |
Subsidiaries:
|
| 1. |
Silexion. Silexion was incorporated in Israel and began its operations on November 30, 2008. Since its incorporation, Silexion has been engaged in one operating segment - the research and development of innovative treatments for pancreatic cancer based on siRNAs, aiming to stop the production of a specific pancreatic cancer-causing protein known as the KRAS mutation. Silexion’s long-lived assets are located in Israel.
|
| 2. |
Silenseed (China) Ltd. On April 28, 2021, Silexion (as the predecessor entity to the Company) signed an agreement with Guangzhou Sino-Israel Biotech Investment Fund (“GIBF”) to establish a new company in China. On June 15, 2021 a company was established in China, named Silenseed (China) Ltd. (hereinafter - the “Chinese Subsidiary”). As of December 31, 2024, following transfer of all interests in the Chinese Subsidiary to the Company as part of the Transactions, the Company owns (directly or indirectly) 100% of the shares of the Chinese Subsidiary. The Chinese Subsidiary has no significant operations as of December 31, 2024.
|
| 3. |
Moringa. Prior to the Transactions (commencing on February 17, 2021), Moringa’s class A ordinary shares and warrants were listed for trading on the Nasdaq Capital Market (Nasdaq: MACA and MACAW). As part of the Transactions, Moringa merged with a wholly-owned subsidiary of the Company and now serves as an inactive, wholly-owned subsidiary of the Company. Following the Transactions, Moringa is no longer listed for trading on the Nasdaq Capital Market.
|
| 4. |
The Company, the Chinese Subsidiary, Moringa and Silexion are together referred to hereinafter as the “Group”.
|
| d. |
On April 3, 2024, Silexion entered into an Amended and Restated Business Combination Agreement (hereinafter, the “A&R BCA”) with the SPAC, New Silexion, August M.S. Ltd. an Israeli company and wholly-owned subsidiary of New Silexion (“Merger Sub 1”), and Moringa Acquisition Merger Sub Corp, a Cayman Islands exempted company and wholly-owned subsidiary of New Silexion (“Merger Sub 2”). Under the A&R BCA, both Silexion and the SPAC were to become wholly-owned subsidiaries of New Silexion, which was to become a publicly-held, Nasdaq-listed entity (the A&R BCA and related transactions: the “Transactions”).
|
F-9
U.S. DOLLARS IN THOUSANDS, EXCEPT SHARE DATA
| e. |
In connection with the closing of the Transactions, the ordinary shares and warrants of New Silexion are now listed on the Nasdaq Global Market and began trading under the symbols “SLXN” and “SLXNW”, respectively.
|
| f. |
For more information on instruments issued as part of the Transactions, see Note 3.
|
| g. |
The Transactions were accounted for as a reverse recapitalization in accordance with US GAAP. Under this method of accounting, Silexion was treated as the accounting acquirer and the SPAC was treated as the “acquired” company for financial reporting purposes. Silexion was determined to be the accounting acquirer based on evaluation of the following facts and circumstances:
|
F-10
U.S. DOLLARS IN THOUSANDS, EXCEPT SHARE DATA
|
Recapitalization
|
||||
|
Accrued expenses assumed
|
1,329
|
|||
|
Warrants to ordinary shares assumed
|
1,130
|
|||
|
Related Party Promissory Note issued
|
3,288
|
|||
|
Underwriters Promissory Note issued
|
1,336
|
|||
|
Less: Loss upon entering Transactions
|
(4,783
|
)
|
||
|
Effect of reverse recapitalization, net of transaction costs
|
2,300
|
|||
| h. |
On November 22, 2024 and July 16, 2025, the Company announced prospective 1-for-9 and 1-for-15 (respectively) reverse share splits of all of its issued and outstanding, and authorized but unissued, ordinary shares. The reverse share splits resulted in corresponding increases in the par value of the Company’s ordinary shares, from $0.0001 per share to $0.0009 per share, and from $0.0009 per share to $0.0135 per share, respectively. No fractional shares were issued as a result of the reverse share splits, as any fractional share totals to which shareholders became entitled were rounded up to the nearest whole number of shares. The reverse share splits became effective after market close on November 27, 2024 and July 28,2025, and the Company’s ordinary shares began trading on a reverse split-adjusted basis on the Nasdaq Global Market and the Nasdaq Capital Market (with respect to the first and second such reverse share splits, respectively) on November 29, 2024 and July 29, 2025, respectively.
|
| i. |
In October 2023, Hamas terrorists infiltrated Israel’s southern border from the Gaza Strip and conducted a series of attacks on civilian and military targets. Following the attack, Israel’s security cabinet declared war against Hamas and commenced a military campaign against Hamas and other terrorist organizations.
|
F-11
U.S. DOLLARS IN THOUSANDS, EXCEPT SHARE DATA
| j. |
Going concern:
|
F-12
U.S. DOLLARS IN THOUSANDS, EXCEPT SHARE DATA
| a. |
Basis of presentation
|
| b. |
Use of estimates
|
| c. |
Functional currency
|
| d. |
Principles of consolidation
|
| e. |
Cash and cash equivalents
|
F-13
U.S. DOLLARS IN THOUSANDS, EXCEPT SHARE DATA
| f. |
Restricted cash
|
| g. |
Property and equipment:
|
|
%
|
||||
|
Computers
|
33
|
|||
|
Office furniture
|
7-15
|
|||
|
Leasehold improvements
|
*
|
|||
| h. |
Employee rights upon retirement
|
F-14
U.S. DOLLARS IN THOUSANDS, EXCEPT SHARE DATA
| i. |
Fair value measurement
|
| Level 1: |
Quoted prices (unadjusted) in active markets that are accessible at the measurement date for assets or liabilities. The fair value hierarchy gives the highest priority to Level 1 inputs.
|
| Level 2: |
Observable prices that are based on inputs not quoted on active markets, but corroborated by market data or active market data of similar or identical assets or liabilities.
|
| Level 3 |
Unobservable inputs are used when little or no market data is available. The fair value hierarchy gives the lowest priority to Level 3 inputs.
|
| j. |
Financial instruments issued
|
F-15
U.S. DOLLARS IN THOUSANDS, EXCEPT SHARE DATA
| k. |
Contracts over Ordinary Shares
|
| l. |
Promissory Notes
|
| m. |
Redeemable Non-controlling Interest
|
F-16
U.S. DOLLARS IN THOUSANDS, EXCEPT SHARE DATA
| n. |
Share-based compensation
|
| o. |
Research and development expenses
|
| p. |
Leases
|
F-17
U.S. DOLLARS IN THOUSANDS, EXCEPT SHARE DATA
| q. |
Loss per share
|
| r. |
Income taxes:
|
| 1) |
Deferred taxes
|
| 2) |
Uncertainty in income tax
|
| s. |
Concentration of credit risks
|
F-18
U.S. DOLLARS IN THOUSANDS, EXCEPT SHARE DATA
| t. |
Impairment of long-lived assets
|
| u. |
Comprehensive Loss
|
| v. |
Loss Contingencies
|
| w. |
New accounting pronouncements:
|
| 1) |
In November 2023, the FASB issued ASU No. 2023-07 Segment Reporting (Topic 280): Improvements to Reportable Segment Disclosures. The ASU improves reportable segments disclosure requirements, primarily through enhanced disclosures about significant segment expenses. The ASU also requires that a public entity that has a single reportable segment must provide all the disclosures required by the amendments and all existing segment disclosures in Topic 280. The Company adopted the ASU on January 1, 2024 - see Note 15.
|
| 1) |
In November 2024, the FASB issued ASU No. 2024-03 Income Statement—Reporting Comprehensive Income—Expense Disaggregation Disclosures (Subtopic 220-40). The ASU improves the disclosures about a public business entity’s expenses and provides more detailed information about the types of expenses in commonly presented expense captions. The amendments require that at each interim and annual reporting period an entity will, inter alia, disclose amounts of purchases of inventory, employee compensation, depreciation and amortization included in each relevant expense caption (such as cost of sales, SG&A and research and development). The ASU is effective for fiscal years beginning after December 15, 2026, and interim periods within fiscal years beginning after December 15, 2027. Early adoption is permitted. The Company is currently evaluating this ASU to determine its impact on the Company's disclosures.
|
F-19
U.S. DOLLARS IN THOUSANDS, EXCEPT SHARE DATA
| 2) |
In December, 2023, the FASB issued ASU 2023-09, Improvements to Income Tax Disclosures, which requires disclosure of disaggregated income taxes paid, prescribes standard categories for the components of the effective tax rate reconciliation, and modifies other income tax-related disclosures. The ASU will be effective for fiscal years beginning after December 15, 2025, and allows adoption on a prospective basis, with a retrospective option. The Company is in the process of assessing the impacts and method of adoption.
|
| 3) |
In June 2022, the FASB issued ASU 2022-03 “Fair Value Measurement of Equity Securities Subject to Contractual Sale Restrictions”. The ASU clarifies that a contractual restriction on the sale of an equity security is not considered part of the unit of account of the equity security and, therefore, is not considered in measuring its fair value. The ASU also clarifies that an entity cannot, as a separate unit of account, recognize and measure a contractual sale restriction. The ASU also introduces new disclosure requirements for equity securities subject to contractual sale restrictions.
|
| a. |
Underwriters Promissory Note
|
F-20
U.S. DOLLARS IN THOUSANDS, EXCEPT SHARE DATA
| b. |
Sponsor/Related Party Promissory Note
|
| c. |
PIPE Financing
|
| d. |
ELOC Financing
|
F-21
U.S. DOLLARS IN THOUSANDS, EXCEPT SHARE DATA
| e. |
SPAC Warrants
|
F-22
U.S. DOLLARS IN THOUSANDS, EXCEPT SHARE DATA
|
December 31
|
||||||||
|
2024
|
2023
|
|||||||
|
Cost:
|
||||||||
|
Computers
|
$
|
87
|
$
|
75
|
||||
|
Office furniture
|
12
|
2
|
||||||
|
Leasehold improvements
|
-
|
56
|
||||||
|
$
|
99
|
$
|
133
|
|||||
|
Accumulated depreciation:
|
||||||||
|
Computers
|
67
|
55
|
||||||
|
Office furniture
|
2
|
2
|
||||||
|
Leasehold improvements
|
-
|
27
|
||||||
|
$
|
69
|
$
|
84
|
|||||
|
Property and equipment, net
|
$
|
30
|
$
|
49
|
||||
| a. |
On August 15, 2024, Silexion vacated its office spaces and facilities in Israel. On September 8, 2024, an early termination agreement for the operating lease was signed with the landlord, which included a termination penalty. As a result, Silexion derecognized the right-of-use asset and the lease liability in its financial statements, recording a loss of $68 from the lease termination and an additional loss of $16 from the disposal of leasehold improvements.
|
| b. |
On September 26, 2024 Silexion signed a new lease agreement for an office in Israel starting November 1, 2024 and ending on October 31, 2026 (initial term of two years and extension options reasonably certain to be exercised ending October 31, 2028). Silexion will pay quarterly fixed payments to the lessor (including payments for common area maintenance). Lease payments are indexed to the Israeli consumer price index (“CPI”).
|
|
Year Ended December 31,
|
||||||||
|
2024
|
2023
|
|||||||
|
Fixed payments and variable payments that depend on an index or rate:
|
||||||||
|
Office and operational lease expenses
|
$
|
144
|
$
|
131
|
||||
|
Variable lease cost (included in the operating lease costs)
|
$
|
8
|
$
|
9
|
||||
|
Loss from lease termination
|
$
|
68
|
-
|
|||||
|
Total operating lease costs
|
$
|
220
|
$
|
140
|
||||
F-23
U.S. DOLLARS IN THOUSANDS, EXCEPT SHARE DATA
|
Year Ended December 31,
|
||||||||
|
2024
|
2023 | |||||||
|
Office and operational spaces lease expenses
|
$
|
130
|
$
|
101
|
||||
|
Termination penalty
|
$
|
34
|
-
|
|||||
|
Total
|
$
|
164
|
$
|
101
|
||||
|
Year Ended December 31,
|
||||||||
|
2024
|
2023
|
|||||||
|
Operating lease right-of-use assets
|
$
|
530
|
$
|
198
|
||||
|
Operating lease liabilities
|
$
|
526
|
$
|
171
|
||||
|
Weighted average remaining lease term (years)
|
3.84
|
1.58
|
||||||
|
Weighted average discount rate
|
11.28
|
%
|
12.69
|
%
|
||||
|
Operating
lease liabilities
|
||||
|
2025
|
$
|
165
|
||
|
2026
|
167
|
|||
|
2027
|
172
|
|||
|
2028
|
132
|
|||
|
Total undiscounted lease payments
|
$
|
636
|
||
|
Less - imputed interest
|
$
|
110
|
||
|
Present value of lease liabilities
|
$
|
526
|
||
| a. |
Research and development expenses:
|
|
Year ended December 31,
|
||||||||
|
2024
|
2023
|
|||||||
|
Payroll and related expenses
|
$
|
1,231
|
$
|
895
|
||||
|
Share-based compensation expenses
|
2,424
|
78
|
||||||
|
Subcontractors and consultants
|
1,890
|
2,467
|
||||||
|
Materials
|
3
|
13
|
||||||
|
Rent and maintenance
|
205
|
160
|
||||||
|
Travel expenses
|
13
|
37
|
||||||
|
Other
|
49
|
58
|
||||||
|
$
|
5,815
|
$
|
3,708
|
|||||
F-24
U.S. DOLLARS IN THOUSANDS, EXCEPT SHARE DATA
| b. |
General and administrative expenses:
|
|
Payroll and related expenses
|
$
|
1,154
|
$
|
304
|
||||
|
Share-based compensation expenses
|
3,438
|
52
|
||||||
|
Professional services
|
1,632
|
386
|
||||||
|
Depreciation
|
25
|
45
|
||||||
|
Rent and maintenance
|
89
|
86
|
||||||
|
Patent registration
|
43
|
22
|
||||||
|
Travel expenses
|
106
|
31
|
||||||
|
Other
|
269
|
47
|
||||||
|
$
|
6,756
|
$
|
973
|
| c. |
Financial expense, net:
|
|
Change in fair value of financial liabilities measured at fair value (including ELOC) |
$
|
(1,150
|
)
|
$
|
86
|
|||
|
Issuance costs |
52
|
3
|
||||||
|
Loss upon entering Transactions
|
4,783
|
-
|
||||||
|
Interest income, net |
(1
|
)
|
(153
|
)
|
||||
|
Foreign currency exchange loss, net
|
247
|
453
|
||||||
|
Other
|
7
|
6
|
||||||
|
Total financial expense, net
|
$
|
3,938
|
$
|
395
|
| a) |
Regarding the Series A-4 Preferred Shares of Silexion, Silexion issued warrants to acquire 161 Series A-4 Preferred Shares to various investors, with an exercise price of $3,343.80 per share and an expiration date of May 30, 2025. Issuance expenses amounted to $3. On August 6, 2024, all of these warrants were exercised in a ‘cashless’ manner for 62 Preferred A4 shares of Silexion.
|
F-25
U.S. DOLLARS IN THOUSANDS, EXCEPT SHARE DATA
| 1) |
On May 30, 2023, Silexion entered into an agreement to receive an investment in a total amount of $538. In exchange for this investment, Silexion issued 161 Series A-4 Preferred Shares with a par value of NIS 1.35. Issuance expenses amounted to $16.
|
| 2) |
See Note 1(d) for shares issued as part of Transactions.
|
| 3) |
See Note 3(d) for ELOC Financing.
|
| a. |
Cayman Islands
|
| b. |
Corporate taxation of Israeli subsidiary
|
| c. |
Income taxes of Chinese Subsidiary
|
| d. |
Tax loss carryforwards
|
F-26
U.S. DOLLARS IN THOUSANDS, EXCEPT SHARE DATA
|
Year ended December 31
|
||||||||
|
2024
|
2023
|
|||||||
|
Domestic – Israel
|
12,156
|
4,769
|
||||||
|
Foreign
|
||||||||
|
Cayman Islands
|
$
|
4,161
|
$
|
-
|
||||
|
Chinese Subsidiary
|
192
|
307
|
||||||
|
Total
|
$
|
16,509
|
$
|
5,076
|
||||
| e. |
Uncertainty in income tax
|
| f. |
Tax rate reconciliation
|
|
Year ended December 31
|
||||||||
|
2024
|
2023
|
|||||||
|
Loss before income taxes
|
$
|
(16,509
|
)
|
$
|
(5,076
|
)
|
||
|
Statutory tax rate
|
23
|
%
|
23
|
%
|
||||
|
Computed “expected” tax income
|
(3,797
|
)
|
(1,167
|
)
|
||||
|
Exchange rate differences
|
(21
|
)
|
120
|
|||||
|
Non-deductible share-based compensation
|
1,373
|
30
|
||||||
|
Non-deductible financial instruments valuation
|
32
|
21
|
||||||
|
Effect of other non-deductible differences
|
78
|
112
|
||||||
|
Change in valuation allowance
|
1,392
|
922
|
||||||
|
Subsidiaries tax rate differences
|
953
|
(6
|
)
|
|||||
|
Reported taxes on income
|
$
|
10
|
$
|
32
|
||||
F-27
U.S. DOLLARS IN THOUSANDS, EXCEPT SHARE DATA
| g. |
Deferred tax
|
|
December 31
|
||||||||
|
2024
|
2023
|
|||||||
|
Deferred tax assets
|
||||||||
|
Operating loss carryforwards
|
$
|
5,800
|
$
|
4,405
|
||||
|
Research and development
|
902
|
780
|
||||||
|
Accrued expenses
|
104
|
304
|
||||||
|
Bonus accrual
|
52
|
-
|
||||||
|
Lease liability
|
121
|
39
|
||||||
|
Other
|
42
|
25
|
||||||
|
Total deferred tax assets
|
$
|
7,021
|
$
|
5,553
|
||||
|
Deferred tax liabilities
|
||||||||
|
Right of use asset
|
(122
|
)
|
(46
|
)
|
||||
|
Total deferred tax liabilities
|
$
|
(122
|
)
|
$
|
(46
|
)
|
||
|
Valuation allowance
|
$
|
(6,899
|
)
|
$
|
(5,507
|
)
|
||
|
Deferred tax assets, net of valuation allowance
|
$
|
-
|
$
|
-
|
||||
| h. |
Roll forward of valuation allowance:
|
|
Balance as of December 31, 2022
|
$
|
(4,585
|
)
|
|
|
Additions
|
(922
|
)
|
||
|
Balance as of December 31, 2023
|
$
|
(5,507
|
)
|
|
|
Additions
|
(1,392
|
)
|
||
|
Balance as of December 31, 2024
|
$
|
(6,899
|
)
|
| i. |
Income tax assessments
|
F-28
U.S. DOLLARS IN THOUSANDS, EXCEPT SHARE DATA
NOTE 11 - SHARE-BASED COMPENSATION:
| 1) |
Warrants to service provider
|
| 2) |
Employee Stock Option Plan
|
F-29
U.S. DOLLARS IN THOUSANDS, EXCEPT SHARE DATA
|
Number of options
|
Weighted-average
exercise price (in
U.S. dollars)
|
Weighted- average
remaining
contractual term
(in years)
|
Aggregate
intrinsic
value
|
|||||||||||||
|
Outstanding at December 31, 2023
|
3,596
|
584.00
|
4.88
|
316
|
||||||||||||
|
Granted
|
-
|
-
|
-
|
-
|
||||||||||||
|
Exercised
|
(919
|
)
|
0.45
|
0.01
|
490
|
|||||||||||
|
Forfeited
|
(22
|
)
|
907.80
|
6.02
|
-
|
|||||||||||
|
Expired
|
(1,047
|
)
|
607.95
|
-
|
-
|
|||||||||||
|
Outstanding at December 31, 2024
|
1,608
|
897.47
|
7.19
|
*
|
||||||||||||
|
Exercisable at December 31, 2024
|
1,608
|
897.47
|
7.19
|
*
|
||||||||||||
|
Vested and expected to vest at December 31, 2024
|
1,608
|
897.47
|
7.19
|
*
|
||||||||||||
|
Expected volatility
|
74.82
|
%
|
||
|
Assumptions regarding the price of the underlying shares:
|
||||
|
Probability of an IPO scenario (including de-SPAC transaction)
|
67
|
%
|
||
|
Expected time to IPO (including de-SPAC transaction) (years)
|
0.137
|
|||
|
Probability of other liquidation events
|
33
|
%
|
||
|
Expected time to liquidation (years)
|
2.25
|
|||
|
Expected return on Equity
|
22
|
%
|
F-30
U.S. DOLLARS IN THOUSANDS, EXCEPT SHARE DATA
|
Year ended December 31
|
||||||||
|
2024
|
2023
|
|||||||
|
Research and development
|
$
|
2,424
|
$
|
78
|
||||
|
General and administrative
|
3,438
|
52
|
||||||
|
$
|
5,862
|
$
|
130
|
|||||
|
December 31, 2024
|
||||||||
|
Level 3
|
Total
|
|||||||
|
Financial Liabilities
|
||||||||
|
Private Warrants to ordinary shares
|
$
|
2
|
$
|
2
|
||||
|
Promissory Notes
|
$
|
3,965
|
$
|
3,965
|
||||
|
December 31, 2023
|
||||||||
|
Level 3
|
Total
|
|||||||
|
Financial Liabilities
|
||||||||
|
Warrants to preferred shares
|
$
|
200
|
$
|
200
|
||||
|
2024
|
||||||||||||
|
Promissory
Notes
|
Warrants to
preferred shares
|
Private Warrants to
ordinary shares
|
||||||||||
|
Fair value at the beginning of the year
|
$
|
-
|
$
|
200
|
$
|
-
|
||||||
|
Issuance
|
4,622
|
1,130
|
||||||||||
|
Change in fair value
|
(407
|
)
|
134
|
(1,128
|
)
|
|||||||
|
Repayments
|
(250
|
)
|
-
|
-
|
||||||||
|
Conversion to equity
|
-
|
(334
|
)
|
-
|
||||||||
|
Fair value at the end of the year
|
$
|
3,965
|
$
|
-,-
|
$
|
2
|
||||||
|
2023
|
||||
|
Warrants to
preferred shares
|
||||
|
Fair value at the beginning of the year
|
$
|
3
|
||
|
Issuance
|
111
|
|||
|
Change in fair value
|
86
|
|||
|
Fair value at the end of the year
|
$
|
200
|
||
F-31
U.S. DOLLARS IN THOUSANDS, EXCEPT SHARE DATA
F-32
U.S. DOLLARS IN THOUSANDS, EXCEPT SHARE DATA
|
December 31,
|
August 15,
|
|||||||
|
|
2024
|
2024
|
||||||
|
Volatility
|
77.69
|
%
|
80.23
|
%
|
||||
|
Dividend yield
|
0
|
%
|
0
|
%
|
||||
|
Year ended December 31
|
||||||||
|
2024
|
2023
|
|||||||
|
Numerator:
|
||||||||
|
Net loss for the year
|
$
|
16,519
|
$
|
5,108
|
||||
|
Net loss attributable to ordinary shareholders:
|
||||||||
|
Basic and diluted
|
$
|
16,443
|
$
|
4,942
|
||||
|
Denominator:
|
||||||||
|
Weighted-average shares used in computing net loss per share attributable to ordinary shareholders, basic and diluted
|
41,635
|
7,493
|
||||||
|
Net loss per share attributable to ordinary shareholders, basic and diluted
|
$
|
394.94
|
$
|
659.55
|
||||
| - |
Redeemable convertible preferred shares (see Note 9);
|
| - |
Warrants to purchase redeemable convertible preferred shares (see Note 8);
|
| - |
Share-based compensation issuable for substantial consideration (see Note 11);
|
| - |
Warrants to purchase ordinary shares (which were originally SPAC warrants (see Note 3));
|
| - |
Underwriters Promissory Note and Related Party Promissory Note (see Note 3);
|
| - |
ELOC financing (see Note 3);
|
F-33
U.S. DOLLARS IN THOUSANDS, EXCEPT SHARE DATA
| a. |
Transactions:
|
|
Year ended December 31
|
||||||||
|
2024
|
2023
|
|||||||
|
Share-based compensation included in research and development expenses
|
$
|
1,796
|
$
|
69
|
||||
|
Share-based compensation included in general and administrative expenses
|
$
|
2,972
|
$
|
48
|
||||
|
Financial expenses
|
$
|
(1,249
|
)
|
$
|
83
|
|||
| b. |
Balances:
|
|
December 31
|
||||||||
|
2024
|
2023
|
|||||||
|
Non-Current liabilities
|
||||||||
|
Warrants to preferred shares
|
-
|
$
|
186
|
|||||
|
Private warrants to purchase ordinary shares
|
$
|
1
|
-
|
|||||
|
Sponsor Promissory Note
|
$
|
2,961
|
-
|
|||||
|
$
|
2,962
|
$
|
186
|
|||||
| a. |
Segment disclosures
|
F-34
U.S. DOLLARS IN THOUSANDS, EXCEPT SHARE DATA
|
Year ended December 31
|
||||||||
|
2024
|
2023
|
|||||||
|
Clinical trials and other services from R&D-related service providers
|
$
|
1,893
|
$
|
2,480
|
||||
|
Payroll and related expenses, other than share-based compensation
|
2,385
|
1,199
|
||||||
|
Share-based compensation expenses
|
5,862
|
130
|
||||||
|
Depreciation expenses
|
25
|
45
|
||||||
|
Other segment expenses (*)
|
2,406
|
827
|
||||||
|
Operating loss
|
12,571
|
4,681
|
||||||
|
Interest income
|
(28
|
)
|
(153
|
)
|
||||
|
Interest expense |
27 | - | ||||||
|
Other financing expense, net
|
3,939
|
548
|
||||||
|
Income taxes
|
10
|
32
|
||||||
|
Net loss
|
$
|
16,519
|
$
|
5,108
|
||||
|
Segment assets
|
$
|
2,863
|
$
|
5,256
|
||||
|
Expenditures for segment assets
|
(22
|
)
|
(12
|
)
|
||||
| b. |
Entity-Wide disclosures
|
| a. |
Public Offering of Ordinary Shares, Pre-Funded Warrants, and Ordinary Warrants.
|
F-35
U.S. DOLLARS IN THOUSANDS, EXCEPT SHARE DATA
| b. |
Induced Warrant Exercise Transaction
|
| c. |
Partial Conversion and Prospective Retirement of Underwriters Promissory Note
|
| d. |
For information regarding the 1-for-15 reverse share split effected on July 28, 2025, see Note 1(h)
|