Exhibit 10.1

Mike Bavaro Chief Human Resources Officer

August 19, 2025

Meenal Sethna

[Redacted]

Cc: John Rademacher - CEO

Dear Meenal,

We are pleased to offer you the position of Chief Financial Officer at Option Care Health, Inc. (the "Company") reporting to the Company’s Chief Executive Officer. In the CFO role, you will be an Executive Officer of the Company. Your anticipated start date is October 1, 2025.

Below are the terms of your offer should you accept, and satisfy the conditions of, the offer:

Base Salary: Your annual salary will be $655,000.00, less all applicable tax withholdings and benefit deductions, payable per the Company’s regular payroll schedule. As an exempt employee, you are not eligible for overtime compensation.

Annual Bonus: During your employment you will be eligible to receive an annual cash bonus, with the target amount of the bonus equal to 90% of your Base Salary, prorated for calendar year 2025. Any annual bonus will be earned based on the achievement of Company results for the calendar year to which the bonus relates and will be paid no later than March 15 in the year following the end of the calendar year to which it relates. The Company’s determination of actual performance relative to applicable criteria and/or target(s) shall be final and binding for purposes of determining your eligibility for, and the amount of, any annual bonus. For clarity, you will be eligible for a prorated bonus for the fourth quarter of calendar year 2025, based on actual Company results.

Equity Awards: Additionally, you are eligible to participate in the Option Care Health, Inc. Equity Incentive Plan (the “Equity Plan”). You will participate in the annual equity grant program and receive an annual equity award comprised of a combination of restricted stock units (40% of value) and performance stock units (60% of value) at a value commensurate with your role. At the February 2026 meeting of the Compensation Committee of the Company’s Board of Directors (the “Compensation Committee”), management will recommend to the Compensation Committee that you be granted an annual equity award with an aggregate target grant date value of approximately $2,400,000. The terms of any equity grants (e.g., number of shares, vesting schedule) will be subject to the terms and conditions of the Equity Plan and the underlying grant agreement.

Consistent with our 2025 plan design, with respect to the 2026 annual equity award referenced above, the vesting for the restricted stock units is expected to be prorated over a three-year period with one-third vesting each year after the anniversary of the grant; and the vesting for the performance stock units is expected to be three-year cliff vesting based on actual Company performance on key metrics established by the Compensation Committee and measured over the 2026, 2027 and 2028 performance years.

Sign-On Equity Award: Management will recommend to the Compensation Committee that the Company award you a Sign-On Equity Award with a grant date value of $1,500,000 comprised of restricted stock units. This equity award will have a three-year cliff vesting schedule. The terms of the Sign-On Equity Award (e.g., number of shares, vesting schedule) will be subject to the terms and conditions of the Equity Plan, the underlying grant agreement and the Company’s Amended and Restated Executive Severance Plan (the “Severance Plan”), and the Severance Plan will govern in the event of conflict with other agreements. For the avoidance of doubt, the Sign-On Equity Award constitutes a “time-based restricted stock unit award” for purposes of Sections 6(c)(i) and 7(c)(i) of the Severance Plan and will be subject to accelerated vesting and settlement in accordance with the terms and limitations contained therein.

Employee Benefits: You will be eligible to participate in such Company employee benefit plans and policies, and to receive such other fringe benefits, as the Company may in its discretion make available to its employees generally, subject to all present and future terms and conditions of such benefit plans and other fringe benefits. These plans and benefits may change or be terminated at any time, for any reason, with or without notice, by the Company in its sole discretion. Please see the enclosed Benefit Offering packet enclosed with this Offer Letter. You will have up to 30 days from your start date to register for any Company sponsored benefit plans.

Commitment to the Business; Policy Compliance: If you accept this offer, we expect that you will perform the duties assigned to you and that you will devote your full business time, attention and effort to your responsibilities for the Company and to perform your assigned responsibilities faithfully and to the best of your abilities. You also will be expected to read and comply with all Company policies and procedures (as in effect or amended from time to time), including the Company’s clawback policies, policies regarding stock ownership by senior executives and policies regarding trading of securities. This letter, along with the Covenants Agreement, is the full and complete agreement between you and the Company with respect to the terms of your at-will employment with the Company and supersedes all prior or contemporaneous negotiations, understandings, or agreements, whether written or oral.

Executive Severance Plan: You are eligible to participate in the Severance Plan. Please review the Severance Plan document included with this Offer Letter and sign and return the Option Care Health Executive Severance Plan Participation Notice and Agreement.

This offer of employment is contingent upon successful passage of the Company’s pre-employment drug and alcohol screening, background investigation, as permitted by law, your provision of proof of eligibility to work in the United States, as well as your agreement to the attached Option Care Health Non-Competition, Non-Solicitation and Confidentiality Agreement. As set forth in the agreement, you have at least 14 days to review and consider the agreement.

At-Will Employment: Your employment with the Company is for no specified period and constitutes at-will employment, meaning that either you or the Company will be entitled to terminate your employment at any time and for any or no reason, with or without notice and with or without cause. Any contrary representations that may have been made to you are superseded by this offer. Your "at-will" status with the Company cannot be modified or amended except by a written agreement, signed by an authorized agent of the Company and you. Although your job duties, title, compensation and benefits, as well as the Company’s personnel policies and procedures may change from time to time, the “at-will” nature of your employment may only be changed in an express written agreement signed by you and the CEO or CHRO of the Company.

No Conflict: By accepting this letter, you represent and warrant that you are not bound by any employment contract, restrictive covenant, or other restriction preventing you from carrying out your responsibilities to the Company, or which is in any way inconsistent with the terms of this offer letter. By accepting this letter, you further represent and warrant that you shall not disclose to the Company or induce the Company to use any confidential or proprietary information or material belonging to any previous employer or others.

Please contact me directly if you have any questions about this offer.

If you would like to accept this offer of employment, please sign your name on the line below, fill in the date, and return the signed letter via email by no later than August 19th. Your signature will acknowledge that you have read, understood, and agreed to the terms and conditions of this offer letter.

Sincerely,

Mike Bavaro

I have read and understood this offer letter and hereby acknowledge, accept and agree to the terms as set forth above and further acknowledge that no other commitments were made to me as part of my employment offer except as specifically set forth herein. I understand that employment in this new role would be at-will and that this document is not intended to create a contract of employment or alter the fact that employment is at-will.

Exhibit 10.2

TRANSITION AGREEMENT AND RELEASE

This agreement (“Agreement”) is entered into between Michael Shapiro (“Employee”) and Option Care Enterprises, Inc. (“Option Care”).

1.              Transition and Separation from Employment.

(a)            Transition and Separation from Employment. Effective as of October 1, 2025 (“Transition Date”), Employee shall step down from Employee’s position as Chief Financial Officer of Option Care Health, Inc. (“OPCH”) and his officer positions with OPCH and Option Care and shall be relieved of all duties with respect to OPCH, Option Care and their affiliates, except as otherwise set forth herein. For the period between the Transition Date and March 31, 2026 (except as otherwise set forth below, the “Termination Date,” and such period, the “Transition Period”), Employee shall be considered a non-executive employee of Option Care, serving as “Special Advisor” to the Chief Executive Officer of Option Care, during which period Employee’s duties shall include consulting on transition matters relating to Employee’s prior duties to Option Care as well as other duties requested by the Chief Executive Officer of Option Care. The parties expect that Employee’s duties during the Transition Period generally shall require Employee to provide services in excess of 33% of the average level of services performed by Employee during Employee’s employment with the Company prior to the Transition Date. Effective on the Termination Date, unless otherwise agreed to by the parties, Employee shall be deemed to have resigned, without any further action by Employee, from any and all positions that Employee holds with Option Care, OPCH, and any of their affiliates. For the avoidance of doubt, Employee’s transition to the role of Special Advisor on the Transition Date, and the related changes to Employee’s compensation and benefits as described herein, shall not constitute “Good Reason” for purposes of the Option Care Health, Inc. Amended and Restated Executive Severance Plan (the “Severance Plan”), and Employee shall not be entitled to any benefits under the Severance Plan or the Employment Agreement, dated as of October 13, 2015, between Walgreens Infusion Services, Inc. and Employee (the “Employment Agreement”) in connection with the termination of Employee’s employment as contemplated herein.

(b)            Accelerated Employment Termination. Notwithstanding Section 1(a), Option Care may accelerate Employee’s Termination Date to (and thus the Transition Period will end on) a date prior to March 31, 2026 designated by Option Care if Employee fails to materially comply with the terms of this Agreement or the Board of Directors of OPCH determines that Employee committed acts that would entitle Option Care to terminate Employee’s employment for “Cause” (as defined in the Severance Plan); provided, that Employee shall be entitled to notice and an opportunity to cure any failure to materially comply with the terms of this Agreement (if curable), provided that if such act or omission is not cured to the Board of Directors of OPCH’s reasonable satisfaction within 30 days after written notice thereof to Employee, then Option Care shall have grounds to terminate Employee pursuant to this Section 1(b). In such event, Employee will not be entitled to any Transition Benefits as set forth herein and will only be entitled to that portion of the salary and benefits that Employee accrues prior to the accelerated date of termination.

(c)            Extension. Notwithstanding any language in this Agreement to the contrary, Option Care and Employee may mutually agree to delay the Termination Date and extend the Transition Period by two consecutive six-month terms.

2.              Transition Benefits. Subject to Employee not resigning during the Transition Period, the Company not terminating Employee’s employment pursuant to Section 1(b) hereof, and provided Employee signs without revocation this Agreement and Employee complies with and does not breach this Agreement (including, without limitation, Sections 5-12 and 14-24 of the Employment Agreement as set forth in Section 4 below), then during the Transition Period: (i) Employee shall continue to be an Option Care employee and shall receive a base salary at an annualized rate of $246,000, paid in accordance with Option Care’s ordinary payroll practices; (ii) subject to Employee’s continued employment through the earlier of March 31, 2026 and the date on which payments under the MIP for fiscal year 2025 are made to other similarly situated employees, Employee shall continue to be eligible for a bonus under the Option Care Health, Inc. Management Incentive Plan (the “MIP”) for fiscal year 2025; provided, that the portion of such bonus attributable to Employee’s service during the Transition Period shall be calculated based on the base salary paid to Employee during the Transition Period; (iii) Employee shall continue to participate in any welfare or retirement benefit plans in which Employee participated as of the Transition Date, subject to the eligibility and other terms and conditions of each such benefit plan; and (iv) Employee’s outstanding equity awards under the Option Care Health, Inc. Amended and Restated 2018 Equity Incentive Plan shall remain outstanding and shall continue to vest and be settled in accordance with their terms based on Employee’s continued status as an employee of the Company through the expiration of the Transition Period, with the post-termination exercise period for any outstanding options commencing as of the Termination Date. For the avoidance of doubt, Employee shall not be eligible for a bonus under the MIP for fiscal year 2026. The benefits described in this Section 2 are referred to herein as the “Transition Benefits.”

3.              Release of Claims. In consideration of the benefits provided to Employee in this Agreement, Employee, for Employee personally and Employee’s representatives, heirs, executors, administrators, successors and assigns, fully, finally and forever releases and discharges Option Care and its affiliates, as well as their respective successors, assigns, officers, owners, directors, agents, representatives, attorneys, insurers, and employees (“Released Parties”), of and from all claims, demands, actions, causes of action, suits, damages, losses, and expenses, of any and every nature whatsoever, individually or as part of a group action, known or unknown, as a result of actions or omissions occurring through the date Employee signs this Agreement. Specifically included in this waiver and release are, among other things, claims of unlawful discrimination, harassment, retaliation, or failure to accommodate; related to terms and conditions of employment; for compensation or benefits; and/or for wrongful termination of employment, under Title VII of the Civil Rights Act of 1964, the Americans with Disabilities Act, the Civil Rights Act of 1866, the Employee Retirement Income Security Act (ERISA), the Age Discrimination in Employment Act (ADEA), the Family and Medical Leave Act (FMLA), the National Labor Relations Act (NLRA), the Uniformed Services Employment and Reemployment Rights Act, the Worker Adjustment and Retraining Notification Act, any amendments to the foregoing, or any other federal, state or local statute, rule, ordinance, or regulation (in each case as amended), as well as claims in equity or under the common law for tort, breach of contract, wrongful discharge, defamation, emotional distress, and negligence or other unlawful behavior.

Nothing in this Agreement is intended to waive claims (a) for unemployment or workers’ compensation benefits, (b) for vested rights under employee compensation and benefit plans as applicable on the date Employee signs this Agreement, (c) that may arise after the date Employee signs this Agreement, (d) for reimbursement of expenses under Option Care’s expense reimbursement policies, or (e) which cannot be released by private agreement.

4.              Continuing Obligations. The Employment Agreement is hereby terminated, null and void except that Sections 5-12 and 14-24 of the Employment Agreement shall continue in full force and effect in accordance with their respective terms, and Employee hereby reaffirms his commitment to comply in full with all such obligations, and except as otherwise provided in Section 9 below.

5.              Non-Admission. This Agreement shall not be construed as an admission by any Released Party of any liability or acts of wrongdoing or unlawful discrimination, nor shall it be evidence of such liability, wrongdoing, or unlawful discrimination.

6.              Non-Disparagement. Except as provided in Section 9 below, Employee agrees not to make, publicly or privately, statements to clients, customers, suppliers, or current and former employees of Option Care or to other members of the public that are slanderous, maliciously false, defamatory, abusive, threatening, harassing, or discriminatory toward Option Care or its products and services.

7.              Advice of Counsel, Consideration and Revocation Periods, Other Information. Option Care hereby advises Employee to consult with an attorney (of his choosing and at his cost) prior to signing this Agreement. Employee has 21 days to consider whether to sign this Agreement from the date Employee receives this Agreement and any attached information (“Consideration Period”). If Employee signs and returns this Agreement before the end of the Consideration Period, it is because Employee freely chose to do so after carefully considering its terms, and Employee knowingly and voluntarily waives the remainder of the Consideration Period. Employee further agrees that Option Care has made no threats or promises to induce Employee to sign earlier. Additionally, Employee shall have seven days from the date the Employee signs this Agreement to revoke this Agreement (“Revocation Period”). If the Revocation Period expires on a weekend or holiday, Employee will have until the end of the next business day to revoke. This Agreement will become effective on the day after the end of the Revocation Period, provided Employee does not revoke this Agreement (“Effective Date”). Employee should return a signed copy of this Agreement and any written revocation by hand delivery, mail or email to the person identified below. Employee agrees with Option Care that changes, whether material or immaterial, do not restart the running of the Consideration Period.

8.              Applicable Law and General Provisions. This Agreement shall be interpreted under the law of the state of Illinois. This Agreement (including any surviving provisions of the Employment Agreement as set forth in Section 4 above) and any attached information sets forth the entire agreement between the parties. Employee is not relying on any other agreements or oral representations not addressed in this document. Any prior agreements between or directly involving Employee and Option Care (including, for the avoidance of doubt, the Employment Agreement except as otherwise provided in Section 4 above) are superseded by this Agreement, except Employee’s obligations under previously signed agreements related to inventions, business ideas, confidentiality of corporate information, restrictive covenants, unfair competition, cooperation, and arbitration or other dispute resolution programs remain intact. The provisions of this Agreement are severable, and if any part of this Agreement except the release of claims is found by a court or arbitrator of competent jurisdiction to be unenforceable, the remainder of this Agreement will continue to be valid and effective. This Agreement may only be amended in a writing signed by all parties (except as set forth in the preceding sentence). The headings in this Agreement are for reference only and shall not affect the substance of this Agreement.

9.              Protected Rights. Nothing in this Agreement, including but not limited to the acknowledgements, release of claims, the proprietary information, confidentiality, non-disparagement, and the return of property provisions (a) limits or affects Employee’s right to disclose or discuss sexual harassment or sexual assault disputes; (b) limits or affects Employee’s right to challenge the validity of this Release under the ADEA or the Older Workers Benefit Protection Act; (c) prevents Employee from communicating with, filing a charge or complaint with, providing documents or information voluntarily or in response to a subpoena or other information request to, or from participating in an investigation or proceeding conducted by, the Equal Employment Opportunity Commission, National Labor Relations Board, the Securities and Exchange Commission, law enforcement, or any other any federal, state or local agency charged with the enforcement of any laws; or from testifying, providing evidence, or responding to a subpoena or discovery request in court litigation or arbitration; (d) prevents a non-management, non-supervisory employees from engaging in protected concerted activity under §7 of the NLRA or similar state law such as joining, assisting, or forming a union, bargaining, picketing, striking, or participating in other activity for mutual aid or protection, or refusing to do so; this includes using or disclosing information acquired through lawful means regarding wages, hours, benefits, or other terms and conditions of employment, unless the information was entrusted to the employee in confidence by Option Care as part of the employee’s job duties. However, by signing this Release Employee is waiving Employee’s right to recover any individual relief (including any backpay, frontpay, reinstatement or other legal or equitable relief) in any charge, complaint, or lawsuit or other proceeding brought by Employee or on Employee’s behalf by any third party, except for any right Employee may have to receive a payment or award from a government agency (and not Option Care) for information provided to the government agency or where otherwise prohibited.

10.              Voluntary Release. Employee acknowledges that, by Employee’s free and voluntary act of signing below, Employee agrees to all of the terms of this Agreement and intends to be legally bound thereby.

IN WITNESS WHEREOF, the undersigned have executed this Agreement, to be effective on the Effective Date.

Exhibit 99.1

Option Care Health Announces Chief Financial Officer Transition

Mike Shapiro to Step Down After 10 Years With the Company; Meenal Sethna Named EVP and CFO
Effective October 1, 2025

BANNOCKBURN, Ill., August 20, 2025 – Option Care Health, Inc. (the “Company” or “Option Care Health”) (Nasdaq: OPCH), the nation’s largest independent provider of home and alternate site infusion services, announced the appointment of Meenal Sethna as Executive Vice President and Chief Financial Officer, effective October 1, 2025. Sethna will succeed Mike Shapiro, who has decided to step down as CFO effective September 30, 2025, following a decade of service to the Company. At the time of the transition, Shapiro will remain with the Company as a Strategic Advisor through at least the first quarter of 2026 to continue to help advance the Company’s strategy and ensure a smooth transition.

Sethna is a seasoned public company CFO and business executive with more than 30 years of broad experience across multiple industries. Sethna most recently served as Executive Vice President and Chief Financial Officer of Littelfuse, Inc., a diversified, industrial technology manufacturing company, where she was responsible for finance and accounting, tax and treasury, investor relations, digital and information technology and supply chain operations. Prior to joining Littelfuse in May 2015, Sethna served as Vice President and Corporate Controller at Illinois Tool Works.

“We are excited to welcome Meenal to the Option Care Health leadership team,” said John C. Rademacher, President and Chief Executive Officer. “She brings significant leadership and a history of thoughtful capital deployment, with a proven track record of driving sustainable growth, enhanced profitability and leading shareholder returns. Option Care Health has tremendous momentum underway, and I look forward to partnering with Meenal as we work to deliver extraordinary care to our patients and create long-term value for our shareholders.”

“Mike has been an incredible partner and a key member of the leadership team since Option Care Health became an independent company. I respect his decision to step down as he begins the next phase of his life,” said Rademacher. “Among his many contributions during his tenure, Mike has helped to build Option Care Health into a leading provider for infusion therapy services, strengthened our financial position and developed a deep bench of finance talent, all while helping navigate through a dynamic healthcare environment. On behalf of the entire organization, I thank him for his service as CFO and appreciate his commitment to our mission as he transitions into an advisory role.”

“After ten rewarding years in the role of CFO, I realize now is the right time to step down for personal reasons. Option Care Health has a solid balance sheet and capital structure with the capacity to continue executing our value creation strategy and strong business performance with the support of an outstanding finance team. I look forward to continuing to work closely with John, Meenal and the leadership team to support the Company’s ongoing success.” said Shapiro.

“I’m inspired by Option Care Health’s purpose to provide extraordinary care that changes lives and I’m honored to be joining the Company,” said Sethna. “Working alongside John and the Option Care Health leadership team, I look forward to building on the Company’s strong foundation and playing a meaningful role in delivering continued growth and further value creation for our shareholders.”

About Meenal Sethna

Sethna most recently served as Executive Vice President and Chief Financial Officer of Littelfuse, Inc. (NASDAQ: LFUS), a diversified, industrial technology manufacturing company, where she was responsible for finance and accounting, tax and treasury, investor relations, digital and information technology and supply chain operations. Prior to joining Littelfuse in May 2015, Sethna spent four years at Illinois Tool Works as Vice President and Corporate Controller. Before that, she worked at Motorola Inc., most recently as Vice President, Finance, and began her career at Baxter International where she held a variety of finance roles during her tenure. She currently serves on the Board of Directors of SPX Technologies.

Sethna is a graduate of the Kellogg School of Management at Northwestern University and the University of Illinois-Urbana and is a Certified Public Accountant in Illinois.

About Option Care Health

Option Care Health is the nation’s largest independent provider of home and alternate site infusion services. With over 8,000 team members including more than 5,000 clinicians, we work compassionately to elevate standards of care for patients with acute and chronic conditions in all 50 states. Through our clinical leadership, expertise and national scale, Option Care Health is reimagining the infusion care experience for patients, customers and team members. To learn more, please visit our website at optioncarehealth.com.

Investor Contact:

Nicole Maggio

nicole.maggio@optioncare.com

312.940.2495